Validation, measurement uncertainty estimation and evaluation of UHPLC greenness for simultaneous determination of metoprolol tartrate and hydrochlorothiazide in binary tablet

Validation, measurement uncertainty estimation and evaluation of UHPLC greenness for simultaneous determination of metoprolol tartrate and hydrochlorothiazide in binary tablet

A novel green ultra high performance liquid chromatography (UHPLC) method was validated and estimated the measurement uncertainty for simultaneous determination of metoprolol tartrate (MET) and hydrochlorothiazide (HCT) in binary tablet. A Zorbax® SB-C18 column with isocratic elution (flow rate 0.9 ...

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Bibliographic Details
Main Authors:	Claudia Vilela de Oliveira, Adriano Peron, Anas Rashid, Frank Alonso Gavilano Fajardo, Felipe Rebello Lourenço, Marina Franco Maggi Tavares, María Segunda Aurora Prado
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Series:	Journal of Taibah University for Science
Subjects:	UHPLC metoprolol tartrate hydrochlorothiazide measurement uncertainty greenness
Online Access:	https://www.tandfonline.com/doi/10.1080/16583655.2024.2339010
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