Dry eye disease and its treatment in women over 45 years

<p> <b>E.A. Drozdova<sup>1</sup>, V.E. Balan<sup>2</sup></b> </p> <p> <b><sup>1</sup>South Ural State Medical University, Chelyabinsk, Russian Federation</b> </p> <p> <b><sup>2</sup>Moscow...

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Main Authors: E.A. Drozdova, V.E. Balan
Format: Article
Language:Russian
Published: Prime-Media 2021-05-01
Series:РМЖ "Клиническая офтальмология"
Online Access:http://clinopht.com/upload/iblock/4f4/4f43be98348d8e48a4cf58627ee0be60.pdf
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author E.A. Drozdova
V.E. Balan
author_facet E.A. Drozdova
V.E. Balan
author_sort E.A. Drozdova
collection DOAJ
description <p> <b>E.A. Drozdova<sup>1</sup>, V.E. Balan<sup>2</sup></b> </p> <p> <b><sup>1</sup>South Ural State Medical University, Chelyabinsk, Russian Federation</b> </p> <p> <b><sup>2</sup>Moscow Regional Research Institute of Obstetrics &amp; Gynecology, Moscow, <br> &nbsp; Russian Federation</b> </p> <p> <i>Epidemiological studies demonstrate an increase in age-related prevalence of dry eye disease (DED) and its higher occurrence in women. In addition to age-related alterations of structures producing tear film, the reduction of androgen levels and other regulating hormones is important for DED development. The role of estrogens and progesterone in the regulation of lacrimal and meibomian gland activity is still disputable. Additional factors of DED development in women are a high rate of comorbidities affecting gland functions, use of cosmetics and cosmetic procedures, contact lens wearing. The results are partial atrophy of meibomian glands, changes in the quality and amount of their secret, increased tear evaporation. Cationic nano-emulsion that addresses the deficiency and stabilize the lipid layer, increases water content, and reduces tear osmolarity is recommended for DED in women.</i> </p> <p> <i><b>Keywords</b>: dry eye disease, tear film, meibomian glands, postmenopausal, lipid layer, tear&nbsp; osmolarity, artificial tears, cationic nano-emulsion.</i> </p> <p> <i><b>For citation: </b>Drozdova E.A., Balan V.E. Dry eye disease and its treatment in women over 45 years. Russian Journal of Clinical Ophthalmology. 2021;21(2):–107. DOI: 10.32364/2311-7729-2021-21-2-103-107.</i> </p>
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spelling doaj-art-c19c9c8e10eb43de9d6dd788891f01072025-01-16T09:39:38ZrusPrime-MediaРМЖ "Клиническая офтальмология"2311-77292619-15712021-05-0121231277Dry eye disease and its treatment in women over 45 yearsE.A. Drozdova0V.E. Balan1Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399<p> <b>E.A. Drozdova<sup>1</sup>, V.E. Balan<sup>2</sup></b> </p> <p> <b><sup>1</sup>South Ural State Medical University, Chelyabinsk, Russian Federation</b> </p> <p> <b><sup>2</sup>Moscow Regional Research Institute of Obstetrics &amp; Gynecology, Moscow, <br> &nbsp; Russian Federation</b> </p> <p> <i>Epidemiological studies demonstrate an increase in age-related prevalence of dry eye disease (DED) and its higher occurrence in women. In addition to age-related alterations of structures producing tear film, the reduction of androgen levels and other regulating hormones is important for DED development. The role of estrogens and progesterone in the regulation of lacrimal and meibomian gland activity is still disputable. Additional factors of DED development in women are a high rate of comorbidities affecting gland functions, use of cosmetics and cosmetic procedures, contact lens wearing. The results are partial atrophy of meibomian glands, changes in the quality and amount of their secret, increased tear evaporation. Cationic nano-emulsion that addresses the deficiency and stabilize the lipid layer, increases water content, and reduces tear osmolarity is recommended for DED in women.</i> </p> <p> <i><b>Keywords</b>: dry eye disease, tear film, meibomian glands, postmenopausal, lipid layer, tear&nbsp; osmolarity, artificial tears, cationic nano-emulsion.</i> </p> <p> <i><b>For citation: </b>Drozdova E.A., Balan V.E. Dry eye disease and its treatment in women over 45 years. Russian Journal of Clinical Ophthalmology. 2021;21(2):–107. DOI: 10.32364/2311-7729-2021-21-2-103-107.</i> </p>http://clinopht.com/upload/iblock/4f4/4f43be98348d8e48a4cf58627ee0be60.pdf
spellingShingle E.A. Drozdova
V.E. Balan
Dry eye disease and its treatment in women over 45 years
РМЖ "Клиническая офтальмология"
title Dry eye disease and its treatment in women over 45 years
title_full Dry eye disease and its treatment in women over 45 years
title_fullStr Dry eye disease and its treatment in women over 45 years
title_full_unstemmed Dry eye disease and its treatment in women over 45 years
title_short Dry eye disease and its treatment in women over 45 years
title_sort dry eye disease and its treatment in women over 45 years
url http://clinopht.com/upload/iblock/4f4/4f43be98348d8e48a4cf58627ee0be60.pdf
work_keys_str_mv AT eadrozdova dryeyediseaseanditstreatmentinwomenover45years
AT vebalan dryeyediseaseanditstreatmentinwomenover45years