ZDHHC20 mediated S-palmitoylation of fatty acid synthase (FASN) promotes hepatocarcinogenesis

ZDHHC20 mediated S-palmitoylation of fatty acid synthase (FASN) promotes hepatocarcinogenesis

Abstract Background Protein palmitoylation is a reversible fatty acyl modification that undertakes important functions in multiple physiological processes. Dysregulated palmitoylations are frequently associated with the formation of cancer. How palmitoyltransferases for S-palmitoylation are involved...

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Bibliographic Details
Main Authors: Yaqi Mo, Yamei Han, Yang Chen, Chunling Fu, Qing Li, Zhuang Liu, Mingming Xiao, Bo Xu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Cancer
Subjects:
Hepatocarcinogenesis
S-palmitoylation
ZDHHC20
FASN
Online Access:https://doi.org/10.1186/s12943-024-02195-5
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