Parkinson Disease ‐Targeted Nanocapsules for Synergistic Treatment: Combining Dopamine Replacement and Neuroinflammation Mitigation

Parkinson Disease ‐Targeted Nanocapsules for Synergistic Treatment: Combining Dopamine Replacement and Neuroinflammation Mitigation

Abstract Parkinson's disease (PD) is characterized by dopamine (DA) neuron loss and neuroinflammation. This study develops carrier‐free nanocapsules (NCs) for targeted delivery of DA and catalase (CAT) to the PD brain, addressing both DA depletion and neuroinflammation simultaneously. The NCs a...

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Bibliographic Details
Main Authors: Ziyao Liu, Shijun Xiang, Bei Chen, Jian Li, Dingcheng Zhu, Hongjuan Xu, Shuo Hu
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
carrier‐free delivery system
macromolecule delivery
neurotransmitter delivery
Parkinson disease
synergistic therapy
Online Access:https://doi.org/10.1002/advs.202404717
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