FPR3 orchestrates macrophage polarization in breast cancer: multi-omics dissection of prognostic relevance and therapeutic targeting

FPR3 orchestrates macrophage polarization in breast cancer: multi-omics dissection of prognostic relevance and therapeutic targeting

Abstract Background The N-formyl peptide receptor family (FPRs) is implicated in the progression of diverse cancer types, yet studies specifically exploring their roles in breast cancer remain scarce. Methods A comprehensive analysis integrating bulk RNA-seq transcriptomics, methylomics, single-cell...

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Bibliographic Details
Main Authors: Ying Chen, Xin Tang, Liran Zhu, Yi Wang, Gaopeng Li, Wulin Yang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Cancer Cell International
Subjects:
FPR3
Breast cancer
Macrophage polarization
Immunity
Online Access:https://doi.org/10.1186/s12935-025-03942-4
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