Exploring the anti-inflammatory effects of curcumin encapsulated within ferritin nanocages: a comprehensive in vivo and in vitro study in Alzheimer’s disease

Exploring the anti-inflammatory effects of curcumin encapsulated within ferritin nanocages: a comprehensive in vivo and in vitro study in Alzheimer’s disease

Abstract Background The global demographic shift towards an aging population is generating a rise in neurodegenerative conditions, with Alzheimer’s disease (AD) as the most prominent problem. In this landscape, the use of natural supplements has garnered attention for their potential in dementia pre...

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Main Authors: Carlo Morasso, Marta Truffi, Veronica Tinelli, Polychronis Stivaktakis, Rosalinda Di Gerlando, Dragoni Francesca, Giulia Perini, Mahvish Faisal, Jana Aid, Bekzod Noridov, Benjamin Lee, Linda Barbieri, Sara Negri, Dragana Nikitovic, Lydia-Nefeli Thrapsanioti, Aristides Tsatsakis, Cristina Cereda, Arianna Bonizzi, Serena Mazzucchelli, Davide Prosperi, Miriam A. Hickey, Fabio Corsi, Stella Gagliardi
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Nanobiotechnology
Subjects:
Curcumin
Nanoparticles
Alzheimer’s disease
H-Ferritin
Blood-brain barrier
5xFAD mice
Online Access:https://doi.org/10.1186/s12951-024-02897-4
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