TET2-mediated 5-hydroxymethylcytosine of TXNIP promotes cell cycle arrest in systemic anaplastic large cell lymphoma

TET2-mediated 5-hydroxymethylcytosine of TXNIP promotes cell cycle arrest in systemic anaplastic large cell lymphoma

Abstract Background 5-Hydroxymethylcytosine (5hmC) modification represents a significant epigenetic modification within DNA, playing a pivotal role in a range of biological processes associated with various types of cancer. The role of 5hmC in systemic anaplastic large cell lymphoma (ALCL) has not b...

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Bibliographic Details
Main Authors: Ziqing Yu, Lihua Zhong, Wangyang Tang, Wenfang Zhang, Ting Lin, Weifeng Zhu, Gang Chen, Jianchao Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Clinical Epigenetics
Subjects:
Anaplastic large cell lymphoma
5-Hydroxymethylcytosine
TET2
TXNIP
Online Access:https://doi.org/10.1186/s13148-025-01816-0
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