Deprescribing anticholinergics to preserve brain health: reducing the risk of dementia through deprescribing (R2D2): study protocol for a randomized clinical trial

Deprescribing anticholinergics to preserve brain health: reducing the risk of dementia through deprescribing (R2D2): study protocol for a randomized clinical trial

Abstract Background Older adults commonly experience chronic medical conditions and are at risk of cognitive impairment as a result of age, chronic comorbidity, and medications prescribed to manage multiple chronic conditions. Anticholinergic medications are common treatments for chronic conditions...

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Main Authors: Noll L. Campbell, Richard J. Holden, Sujuan Gao, Frederick W. Unverzagt, Kathleen A. Lane, Allie Carter, Addison B. Harrington, Sneha Manoharan, Neha Manoharan, Danielle L. Rosenthal, Christopher Pitts, Kathryn Pelkey, Emily Papineau, David M. Lauck, Noha Keshk, Khalid Alamer, Hussein Khalil, Malaz A. Boustani
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Trials
Subjects:
Anticholinergics
Deprescribing
Cognition
Dementia
Online Access:https://doi.org/10.1186/s13063-024-08618-4
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