Synthetic circuits reveal how mechanisms of gene regulatory networks constrain evolution
Abstract Phenotypic variation is the raw material of adaptive Darwinian evolution. The phenotypic variation found in organismal development is biased towards certain phenotypes, but the molecular mechanisms behind such biases are still poorly understood. Gene regulatory networks have been proposed a...
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| Main Authors: | Yolanda Schaerli, Alba Jiménez, José M Duarte, Ljiljana Mihajlovic, Julien Renggli, Mark Isalan, James Sharpe, Andreas Wagner |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2018-09-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/msb.20178102 |
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