Pulmonary Surfactant Function in Alveoli and Conducting Airways

Surface tension plays a very important role in aeration of the neonate's lungs. Pulmonary surfactant, which is inadequate in the premature infant, modifies surface tension during the act of breathing and is necessary for maintenance of alveolar stability. These facts led to the development of t...

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Main Author: Goran Enhorning
Format: Article
Language:English
Published: Wiley 1996-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/1996/364751
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author Goran Enhorning
author_facet Goran Enhorning
author_sort Goran Enhorning
collection DOAJ
description Surface tension plays a very important role in aeration of the neonate's lungs. Pulmonary surfactant, which is inadequate in the premature infant, modifies surface tension during the act of breathing and is necessary for maintenance of alveolar stability. These facts led to the development of the concept that it might be possible to treat the premature infant by supplementing the infant's inadequate surfactant supply. In addition to maintaining alveolar stability, pulmonary surfactant might also be of vital importance for maintenance of small airway patency. Various conditions, most importantly asthma, might be the reason for a surfactant dysfunction to develop. This in turn might cause airway resistance to increase.
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institution Kabale University
issn 1198-2241
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publishDate 1996-01-01
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series Canadian Respiratory Journal
spelling doaj-art-c14b5d22761644e398bf5cea67a7c3612025-02-03T05:53:16ZengWileyCanadian Respiratory Journal1198-22411996-01-0131212710.1155/1996/364751Pulmonary Surfactant Function in Alveoli and Conducting AirwaysGoran EnhorningSurface tension plays a very important role in aeration of the neonate's lungs. Pulmonary surfactant, which is inadequate in the premature infant, modifies surface tension during the act of breathing and is necessary for maintenance of alveolar stability. These facts led to the development of the concept that it might be possible to treat the premature infant by supplementing the infant's inadequate surfactant supply. In addition to maintaining alveolar stability, pulmonary surfactant might also be of vital importance for maintenance of small airway patency. Various conditions, most importantly asthma, might be the reason for a surfactant dysfunction to develop. This in turn might cause airway resistance to increase.http://dx.doi.org/10.1155/1996/364751
spellingShingle Goran Enhorning
Pulmonary Surfactant Function in Alveoli and Conducting Airways
Canadian Respiratory Journal
title Pulmonary Surfactant Function in Alveoli and Conducting Airways
title_full Pulmonary Surfactant Function in Alveoli and Conducting Airways
title_fullStr Pulmonary Surfactant Function in Alveoli and Conducting Airways
title_full_unstemmed Pulmonary Surfactant Function in Alveoli and Conducting Airways
title_short Pulmonary Surfactant Function in Alveoli and Conducting Airways
title_sort pulmonary surfactant function in alveoli and conducting airways
url http://dx.doi.org/10.1155/1996/364751
work_keys_str_mv AT goranenhorning pulmonarysurfactantfunctioninalveoliandconductingairways