Current research trends and hotspots of boron neutron capture therapy: a bibliometric and visualization analysis
PurposeThis study aimed to describe the trends, current hotspots, and future directions in boron neutron capture therapy (BNCT) through a bibliometric analysis.MethodsArticles related to BNCT published before 2023-12-31 were retrieved from the Web of Science Core Collection database. VOSviewer, R, a...
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Frontiers Media S.A.
2024-12-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1507157/full |
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| author | Yuyang Cong Muyasha Abulimiti Yoshitaka Matsumoto Jing Jin Jing Jin |
| author_facet | Yuyang Cong Muyasha Abulimiti Yoshitaka Matsumoto Jing Jin Jing Jin |
| author_sort | Yuyang Cong |
| collection | DOAJ |
| description | PurposeThis study aimed to describe the trends, current hotspots, and future directions in boron neutron capture therapy (BNCT) through a bibliometric analysis.MethodsArticles related to BNCT published before 2023-12-31 were retrieved from the Web of Science Core Collection database. VOSviewer, R, and CiteSpace were used for bibliometric analysis and visualization.ResultsA total of 3347 related publications from 1975 to 2023 were retrieved. Since a burst of published documents in 1992, the past three decades have witnessed continuous investigations into BNCT-related studies. Japan was the most productive country (794, 23.72%), followed by the USA (792, 23.66%), while the latter had the most citations. Kyoto University was the most influential institution. Ono K was the most prolific author, and Applied Radiation and Isotopes was the most popular journal. Ono K was the author that had the most total citations, followed by Barth RF. “Carborane”, “boronophenylalanine”, “glioblastoma”, “sodium borocaptate”, “cancer” and “drug delivery” were the most frequent keywords. The article “Dendrimers and dendritic polymers in drug delivery” had the most citations, whereas “Boron delivery agents for neutron capture therapy of cancer” had the highest outbreak value.ConclusionOver the past three decades, research on BNCT has expanded significantly, with the development of novel boron carriers with improved medicinal characteristics being the most extensively investigated area. Future research will likely focus on the validation and modification of current BNCT treatment modalities using conventional boron agents in brain tumors, accelerator-based neutron sources and the application of BNCT in more clinical scenarios. |
| format | Article |
| id | doaj-art-c109f6098bfb4e08a215a282dcae574c |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-c109f6098bfb4e08a215a282dcae574c2024-12-12T06:18:37ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2024-12-011410.3389/fonc.2024.15071571507157Current research trends and hotspots of boron neutron capture therapy: a bibliometric and visualization analysisYuyang Cong0Muyasha Abulimiti1Yoshitaka Matsumoto2Jing Jin3Jing Jin4Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, ChinaDepartment of Radiation Oncology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, JapanDepartment of Radiation Oncology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, JapanDepartment of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, ChinaDepartment of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaPurposeThis study aimed to describe the trends, current hotspots, and future directions in boron neutron capture therapy (BNCT) through a bibliometric analysis.MethodsArticles related to BNCT published before 2023-12-31 were retrieved from the Web of Science Core Collection database. VOSviewer, R, and CiteSpace were used for bibliometric analysis and visualization.ResultsA total of 3347 related publications from 1975 to 2023 were retrieved. Since a burst of published documents in 1992, the past three decades have witnessed continuous investigations into BNCT-related studies. Japan was the most productive country (794, 23.72%), followed by the USA (792, 23.66%), while the latter had the most citations. Kyoto University was the most influential institution. Ono K was the most prolific author, and Applied Radiation and Isotopes was the most popular journal. Ono K was the author that had the most total citations, followed by Barth RF. “Carborane”, “boronophenylalanine”, “glioblastoma”, “sodium borocaptate”, “cancer” and “drug delivery” were the most frequent keywords. The article “Dendrimers and dendritic polymers in drug delivery” had the most citations, whereas “Boron delivery agents for neutron capture therapy of cancer” had the highest outbreak value.ConclusionOver the past three decades, research on BNCT has expanded significantly, with the development of novel boron carriers with improved medicinal characteristics being the most extensively investigated area. Future research will likely focus on the validation and modification of current BNCT treatment modalities using conventional boron agents in brain tumors, accelerator-based neutron sources and the application of BNCT in more clinical scenarios.https://www.frontiersin.org/articles/10.3389/fonc.2024.1507157/fullboron neutron capture therapybibliometric analysisresearch trendsVOSviewerCiteSpace |
| spellingShingle | Yuyang Cong Muyasha Abulimiti Yoshitaka Matsumoto Jing Jin Jing Jin Current research trends and hotspots of boron neutron capture therapy: a bibliometric and visualization analysis Frontiers in Oncology boron neutron capture therapy bibliometric analysis research trends VOSviewer CiteSpace |
| title | Current research trends and hotspots of boron neutron capture therapy: a bibliometric and visualization analysis |
| title_full | Current research trends and hotspots of boron neutron capture therapy: a bibliometric and visualization analysis |
| title_fullStr | Current research trends and hotspots of boron neutron capture therapy: a bibliometric and visualization analysis |
| title_full_unstemmed | Current research trends and hotspots of boron neutron capture therapy: a bibliometric and visualization analysis |
| title_short | Current research trends and hotspots of boron neutron capture therapy: a bibliometric and visualization analysis |
| title_sort | current research trends and hotspots of boron neutron capture therapy a bibliometric and visualization analysis |
| topic | boron neutron capture therapy bibliometric analysis research trends VOSviewer CiteSpace |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2024.1507157/full |
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