Are obese rats influenced by GLP1 and IR through aerobic exercise? A case study
The present study aimed to consider the influence of aerobic exercise intensity on GLP-1and IR in obese rats. Glucagon-like peptide-1 (GLP-1) is characterized as incretion hormones secreted from the intestine upon ingestion of food to maximize insulin secretion, regulate blood sugar and enhance insu...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
2016-08-01
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| Series: | Türk Spor ve Egzersiz Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/230080 |
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| author | Ali Sayyah Hamid Mohebbı Hamid Arazı Abbas Baharı |
| author_facet | Ali Sayyah Hamid Mohebbı Hamid Arazı Abbas Baharı |
| author_sort | Ali Sayyah |
| collection | DOAJ |
| description | The
present study aimed to consider the influence of aerobic exercise intensity on
GLP-1and IR in obese rats. Glucagon-like peptide-1 (GLP-1) is characterized as incretion
hormones secreted from the intestine upon ingestion of food to maximize insulin
secretion, regulate blood sugar and enhance insulin resistance (IR). It was an
in vitro study. The study subjects were thirty-two male Wistar rats which were
divided into 4 groups: three levels of aerobic training intensity (high,
moderate and low intensity) and one control group. Following 8 weeks of
different intensity of aerobic trainings, the researchers calculated plasma
concentration of glucose, insulin, HOMA-IR and GLP-1. We applied dependent
t-test and Analysis of variance (ANOVA) to test the research hypotheses. Body
weight, BMI, insulin, blood glucose and HOMA-IR in high,
moderate and low intensity of aerobic training were noticed to be significantly
lower than in the control group (P=0.001) following an eight-week intervention. However, moderate
and high intensity of aerobic training compared with low intensity
significantly showed a decrease in insulin, blood glucose, HOMA-IR, and GLP-1.
The findings revealed that moderate and high intensity of aerobic training
results in GLP-1 secretion impairment, thus its improvement can cause a
reduction in insulin resistance and blood glucose regulation. |
| format | Article |
| id | doaj-art-c0fe0360280e45d3a3be8374039b65ea |
| institution | Kabale University |
| issn | 2147-5652 |
| language | English |
| publishDate | 2016-08-01 |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Türk Spor ve Egzersiz Dergisi |
| spelling | doaj-art-c0fe0360280e45d3a3be8374039b65ea2025-01-03T01:00:34ZengSelcuk University PressTürk Spor ve Egzersiz Dergisi2147-56522016-08-0118217154Are obese rats influenced by GLP1 and IR through aerobic exercise? A case studyAli SayyahHamid MohebbıHamid ArazıAbbas BaharıThe present study aimed to consider the influence of aerobic exercise intensity on GLP-1and IR in obese rats. Glucagon-like peptide-1 (GLP-1) is characterized as incretion hormones secreted from the intestine upon ingestion of food to maximize insulin secretion, regulate blood sugar and enhance insulin resistance (IR). It was an in vitro study. The study subjects were thirty-two male Wistar rats which were divided into 4 groups: three levels of aerobic training intensity (high, moderate and low intensity) and one control group. Following 8 weeks of different intensity of aerobic trainings, the researchers calculated plasma concentration of glucose, insulin, HOMA-IR and GLP-1. We applied dependent t-test and Analysis of variance (ANOVA) to test the research hypotheses. Body weight, BMI, insulin, blood glucose and HOMA-IR in high, moderate and low intensity of aerobic training were noticed to be significantly lower than in the control group (P=0.001) following an eight-week intervention. However, moderate and high intensity of aerobic training compared with low intensity significantly showed a decrease in insulin, blood glucose, HOMA-IR, and GLP-1. The findings revealed that moderate and high intensity of aerobic training results in GLP-1 secretion impairment, thus its improvement can cause a reduction in insulin resistance and blood glucose regulation.https://dergipark.org.tr/tr/download/article-file/230080aerobic exerciseglucagon-like peptide-1swimming exercise |
| spellingShingle | Ali Sayyah Hamid Mohebbı Hamid Arazı Abbas Baharı Are obese rats influenced by GLP1 and IR through aerobic exercise? A case study Türk Spor ve Egzersiz Dergisi aerobic exercise glucagon-like peptide-1 swimming exercise |
| title | Are obese rats influenced by GLP1 and IR through aerobic exercise? A case study |
| title_full | Are obese rats influenced by GLP1 and IR through aerobic exercise? A case study |
| title_fullStr | Are obese rats influenced by GLP1 and IR through aerobic exercise? A case study |
| title_full_unstemmed | Are obese rats influenced by GLP1 and IR through aerobic exercise? A case study |
| title_short | Are obese rats influenced by GLP1 and IR through aerobic exercise? A case study |
| title_sort | are obese rats influenced by glp1 and ir through aerobic exercise a case study |
| topic | aerobic exercise glucagon-like peptide-1 swimming exercise |
| url | https://dergipark.org.tr/tr/download/article-file/230080 |
| work_keys_str_mv | AT alisayyah areobeseratsinfluencedbyglp1andirthroughaerobicexerciseacasestudy AT hamidmohebbı areobeseratsinfluencedbyglp1andirthroughaerobicexerciseacasestudy AT hamidarazı areobeseratsinfluencedbyglp1andirthroughaerobicexerciseacasestudy AT abbasbaharı areobeseratsinfluencedbyglp1andirthroughaerobicexerciseacasestudy |