Self-healable and pH-responsive spermidine/ferrous ion complexed hydrogel Co-loaded with CA inhibitor and glucose oxidase for combined cancer immunotherapy through triple ferroptosis mechanism
Tumor microenvironment governs various therapeutic tolerability of cancer such as ferroptosis and immunotherapy through rewiring tumor metabolic reprogramming like Warburg metabolism. Highly expressed carbonic anhydrases (CA) in tumor that maintaining the delicate metabolic homeostasis is thus the m...
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Main Authors: | Tianqi Nie, Yifei Fang, Ruhe Zhang, Yishui Cai, Xiaobo Wang, Yuenong Jiao, Jun Wu |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2025-05-01
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Series: | Bioactive Materials |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X25000052 |
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