<i>Broussonetia papyrifera</i> Extract Can Be Used as a Raw Material Source for a Sterility Agent for <i>Microtus fortis</i>
Plant sterilants are used to control rodent populations due to their minimal environmental risk and other ethical considerations. However, their practical utilization is unsatisfactory due to high costs and processing difficulties. <i>Broussonetia papyrifera</i> is a plant material that...
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2025-01-01
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| author | Shuangye Wang Tian Lan Yunlin Zhao Wanfu Liu Tian Huang Meiwen Zhang Zhiyuan Hu Zhenggang Xu |
| author_facet | Shuangye Wang Tian Lan Yunlin Zhao Wanfu Liu Tian Huang Meiwen Zhang Zhiyuan Hu Zhenggang Xu |
| author_sort | Shuangye Wang |
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| description | Plant sterilants are used to control rodent populations due to their minimal environmental risk and other ethical considerations. However, their practical utilization is unsatisfactory due to high costs and processing difficulties. <i>Broussonetia papyrifera</i> is a plant material that has shown the potential to inhibit the reproduction of <i>Microtus fortis</i>, a species that causes serious damage to crops in the Dongting Lake region in China. <i>M. fortis</i> was treated with different doses of <i>B. papyrifera</i> leaf methanol extracts. The results show that the growth of sex organs was inhibited, and the males’ testosterone levels and sperm quality were reduced. Though there were some positive effects on females, the reproductive parameters of coupled voles were inferior; the most treated couple exhibited an increased reproductive time, fetal counts, and reduced weight. It was also found that <i>M. fortis</i> responded negatively to the extract after a single treatment or long-term repeated treatment compared to a short-term repeated treatment. <i>B. papyrifera</i> leaves showed a higher application potential as a sterilant for male rodents. These findings enrich the study of plant sterilants and provide insights into the utilization of <i>B. papyrifera</i> and the management of rodents. Owing to the effectiveness and accessibility of the leaves, the derived sterilant may be more economical for controlling rodent pests. |
| format | Article |
| id | doaj-art-c0720b531bb8401f8486f2934da977a8 |
| institution | Kabale University |
| issn | 2079-7737 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
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| series | Biology |
| spelling | doaj-art-c0720b531bb8401f8486f2934da977a82025-01-24T13:23:27ZengMDPI AGBiology2079-77372025-01-011415610.3390/biology14010056<i>Broussonetia papyrifera</i> Extract Can Be Used as a Raw Material Source for a Sterility Agent for <i>Microtus fortis</i>Shuangye Wang0Tian Lan1Yunlin Zhao2Wanfu Liu3Tian Huang4Meiwen Zhang5Zhiyuan Hu6Zhenggang Xu7The Central Laboratory of Medical Molecular Biology, School of Basic Medicine, Guiyang Healthcare Vocational University, Guiyang 550081, ChinaKey Laboratory of National Forestry and Grassland Administration on Management of Western Forest Bio-Disaster, College of Forestry, Northwest A & F University, Yangling 712100, ChinaHunan Research Center of Engineering Technology for Utilization of Environmental and Resources Plant, Central South University of Forestry and Technology, Changsha 410004, ChinaHunan Research Center of Engineering Technology for Utilization of Environmental and Resources Plant, Central South University of Forestry and Technology, Changsha 410004, ChinaHunan Engineering Research Center of Ecological Environment Intelligent Monitoring and Disaster Prevention and Mitigation Technology in Dongting Lake Region, College of Information and Electronic Engineering, Hunan City University, Yiyang 413000, ChinaDongting Lake Station for Wetland Ecosystem Research, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, ChinaHunan Engineering Research Center of Ecological Environment Intelligent Monitoring and Disaster Prevention and Mitigation Technology in Dongting Lake Region, College of Information and Electronic Engineering, Hunan City University, Yiyang 413000, ChinaHunan Engineering Research Center of Ecological Environment Intelligent Monitoring and Disaster Prevention and Mitigation Technology in Dongting Lake Region, College of Information and Electronic Engineering, Hunan City University, Yiyang 413000, ChinaPlant sterilants are used to control rodent populations due to their minimal environmental risk and other ethical considerations. However, their practical utilization is unsatisfactory due to high costs and processing difficulties. <i>Broussonetia papyrifera</i> is a plant material that has shown the potential to inhibit the reproduction of <i>Microtus fortis</i>, a species that causes serious damage to crops in the Dongting Lake region in China. <i>M. fortis</i> was treated with different doses of <i>B. papyrifera</i> leaf methanol extracts. The results show that the growth of sex organs was inhibited, and the males’ testosterone levels and sperm quality were reduced. Though there were some positive effects on females, the reproductive parameters of coupled voles were inferior; the most treated couple exhibited an increased reproductive time, fetal counts, and reduced weight. It was also found that <i>M. fortis</i> responded negatively to the extract after a single treatment or long-term repeated treatment compared to a short-term repeated treatment. <i>B. papyrifera</i> leaves showed a higher application potential as a sterilant for male rodents. These findings enrich the study of plant sterilants and provide insights into the utilization of <i>B. papyrifera</i> and the management of rodents. Owing to the effectiveness and accessibility of the leaves, the derived sterilant may be more economical for controlling rodent pests.https://www.mdpi.com/2079-7737/14/1/56methanolic extract<i>Microtus fortis</i>paper mulberrysterilantsorgan coefficientsperm teratogenicity |
| spellingShingle | Shuangye Wang Tian Lan Yunlin Zhao Wanfu Liu Tian Huang Meiwen Zhang Zhiyuan Hu Zhenggang Xu <i>Broussonetia papyrifera</i> Extract Can Be Used as a Raw Material Source for a Sterility Agent for <i>Microtus fortis</i> Biology methanolic extract <i>Microtus fortis</i> paper mulberry sterilants organ coefficient sperm teratogenicity |
| title | <i>Broussonetia papyrifera</i> Extract Can Be Used as a Raw Material Source for a Sterility Agent for <i>Microtus fortis</i> |
| title_full | <i>Broussonetia papyrifera</i> Extract Can Be Used as a Raw Material Source for a Sterility Agent for <i>Microtus fortis</i> |
| title_fullStr | <i>Broussonetia papyrifera</i> Extract Can Be Used as a Raw Material Source for a Sterility Agent for <i>Microtus fortis</i> |
| title_full_unstemmed | <i>Broussonetia papyrifera</i> Extract Can Be Used as a Raw Material Source for a Sterility Agent for <i>Microtus fortis</i> |
| title_short | <i>Broussonetia papyrifera</i> Extract Can Be Used as a Raw Material Source for a Sterility Agent for <i>Microtus fortis</i> |
| title_sort | i broussonetia papyrifera i extract can be used as a raw material source for a sterility agent for i microtus fortis i |
| topic | methanolic extract <i>Microtus fortis</i> paper mulberry sterilants organ coefficient sperm teratogenicity |
| url | https://www.mdpi.com/2079-7737/14/1/56 |
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