Deep vein thrombosis - the review

Deep vein thrombosis impacts between 2.5% and 5% of a population. It mostly affects lower-extremity veins and presents itself as pain, swelling, tenderness, and erythema of an affected region. Thrombus forms when at least one factor from the Virchow's triad is present - vascular damage, venous...

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Main Authors: Karol Stępniak, Wiktor Telega, Kinga Wnuczek, Joanna Wrona, Aleksandra Kaźmierczyk, Jędrzej Kęsik, Daria Madycka, Kacper Michta, Małgorzata Słaboń, Maciej Sobczyk
Format: Article
Language:English
Published: Nicolaus Copernicus University in Toruń 2024-11-01
Series:Quality in Sport
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Online Access:https://apcz.umk.pl/QS/article/view/56187
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Summary:Deep vein thrombosis impacts between 2.5% and 5% of a population. It mostly affects lower-extremity veins and presents itself as pain, swelling, tenderness, and erythema of an affected region. Thrombus forms when at least one factor from the Virchow's triad is present - vascular damage, venous stasis or hypercoagulability. A range of clinical manifestations is very wide, from asymptomatic to life-threatening course of the disease. Post-thrombotic syndrome is a frequent complication that results in venous hypertension, which leads to tissue edema, subcutaneous fibrosis, and subsequent ulceration. In the diagnostic process, predominantly D-dimer assay and ultrasonographic compression test are performed. Noninvasive treatment relies on anticoagulation therapy which is based on direct oral anticoagulants, parenteral anticoagulants, and vitamin K antagonists. In specific cases, there is an option of invasive treatment, which involves inserting a catheter into a vein with a thrombus. Afterward, a thrombus can be mechanically fragmented and aspired or dissolved with the use of a thrombolytic agent. 
ISSN:2450-3118