Influence of physico-chemical properties of hydroxypropyl methylcellulose on quetiapine fumarate release from sustained release matrix tablets

Abstract Quetiapine fumarateis a typical antipsychotic with a short half-life of 6 h and is administered multiple times daily. In this study, a copolymer for controlled delivery of quetiapine fumarate will be developed. In order to prevent side effects and improve patient compliance, hydroxypropyl m...

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Bibliographic Details
Main Authors: Takwa E. Ellakwa, Ahmad S. Abu-Khadra, Doha El-Sayed Ellakwa
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Chemistry
Subjects:
Online Access:https://doi.org/10.1186/s13065-024-01311-2
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