Continuous prediction for tumor mutation burden based on transcriptional data in gastrointestinal cancers
Abstract Background Tumor mutation burden (TMB) has been considered a biomarker for utilization of immune checkpoint inhibitors(ICIs), but whole exome sequencing(WES) and cancer gene panel(CGP) based on next generation sequencing for TMB detection are costly. Here, we use transcriptome data of TCGA...
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| Main Authors: | Beibei Hu, Guohui Yin, Jialin Zhu, Yi Bai, Xuren Sun |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
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| Series: | BMC Medical Informatics and Decision Making |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12911-024-02794-8 |
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