Associations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005–2006

Abstract Background The health benefits of physical activity, including walking, are well-established, but the relationship between daily step count and mortality in hypertensive populations remains underexplored. This study investigates the association between daily step count and both all-cause an...

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Main Authors: Tuo Guo, Yang Zhou, Guifang Yang, Aifang Zhong, Xiaogao Pan, Yuting Pu, Michael Simons, Lijuan Sheng, Xiangping Chai
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-024-21216-y
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author Tuo Guo
Yang Zhou
Guifang Yang
Aifang Zhong
Xiaogao Pan
Yuting Pu
Michael Simons
Lijuan Sheng
Xiangping Chai
author_facet Tuo Guo
Yang Zhou
Guifang Yang
Aifang Zhong
Xiaogao Pan
Yuting Pu
Michael Simons
Lijuan Sheng
Xiangping Chai
author_sort Tuo Guo
collection DOAJ
description Abstract Background The health benefits of physical activity, including walking, are well-established, but the relationship between daily step count and mortality in hypertensive populations remains underexplored. This study investigates the association between daily step count and both all-cause and cardiovascular mortality in hypertensive American adults. Methods We used data from the National Health and Nutrition Examination Survey 2005–2006, including 1,629 hypertensive participants with accelerometer-measured step counts. Cox proportional hazards models and restricted cubic spline regression were employed to assess the associations between daily step count and mortality outcomes. Analyses were adjusted for demographics, lifestyle factors, and comorbidities. Results Over an average follow-up of 12.57 years, 370 deaths occurred, of which 177 were due to cardiovascular causes. We observed non-linear associations between daily step count and mortality. Mortality risks were significantly reduced with step counts to 8,250 steps/day for all-cause mortality and 9,700 steps/day for cardiovascular mortality. Beyond these thresholds, the benefits plateaued. Conclusion Increasing daily step count is associated with reduced all-cause and cardiovascular mortality in hypertensive individuals, with optimal benefits observed below 8,250 and 9,700 daily steps, respectively. Moderate levels of physical activity provide substantial health benefits, highlighting the importance of setting realistic and attainable activity goals for hypertensive populations.
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spelling doaj-art-c04d5703fda4434baa92b0bb6dc34d042025-01-12T12:42:59ZengBMCBMC Public Health1471-24582025-01-0125111210.1186/s12889-024-21216-yAssociations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005–2006Tuo Guo0Yang Zhou1Guifang Yang2Aifang Zhong3Xiaogao Pan4Yuting Pu5Michael Simons6Lijuan Sheng7Xiangping Chai8Department of Emergency Medicine, The Second Xiangya Hospital, Central South UniversityDepartment of Intensive Care Unit, The Second Xiangya Hospital, Central South UniversityDepartment of Emergency Medicine, The Second Xiangya Hospital, Central South UniversityDepartment of Emergency Medicine, The Second Xiangya Hospital, Central South UniversityDepartment of Emergency Medicine, The Second Xiangya Hospital, Central South UniversityDepartment of Emergency Medicine, The Second Xiangya Hospital, Central South UniversityYale Cardiovascular Research Center, Yale University School of MedicineClinical Nursing Teaching and Research Section, The Second Xiangya Hospital, Central South UniversityDepartment of Emergency Medicine, The Second Xiangya Hospital, Central South UniversityAbstract Background The health benefits of physical activity, including walking, are well-established, but the relationship between daily step count and mortality in hypertensive populations remains underexplored. This study investigates the association between daily step count and both all-cause and cardiovascular mortality in hypertensive American adults. Methods We used data from the National Health and Nutrition Examination Survey 2005–2006, including 1,629 hypertensive participants with accelerometer-measured step counts. Cox proportional hazards models and restricted cubic spline regression were employed to assess the associations between daily step count and mortality outcomes. Analyses were adjusted for demographics, lifestyle factors, and comorbidities. Results Over an average follow-up of 12.57 years, 370 deaths occurred, of which 177 were due to cardiovascular causes. We observed non-linear associations between daily step count and mortality. Mortality risks were significantly reduced with step counts to 8,250 steps/day for all-cause mortality and 9,700 steps/day for cardiovascular mortality. Beyond these thresholds, the benefits plateaued. Conclusion Increasing daily step count is associated with reduced all-cause and cardiovascular mortality in hypertensive individuals, with optimal benefits observed below 8,250 and 9,700 daily steps, respectively. Moderate levels of physical activity provide substantial health benefits, highlighting the importance of setting realistic and attainable activity goals for hypertensive populations.https://doi.org/10.1186/s12889-024-21216-yHypertensionDaily step countMortalityNHANES
spellingShingle Tuo Guo
Yang Zhou
Guifang Yang
Aifang Zhong
Xiaogao Pan
Yuting Pu
Michael Simons
Lijuan Sheng
Xiangping Chai
Associations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005–2006
BMC Public Health
Hypertension
Daily step count
Mortality
NHANES
title Associations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005–2006
title_full Associations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005–2006
title_fullStr Associations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005–2006
title_full_unstemmed Associations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005–2006
title_short Associations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005–2006
title_sort associations of daily step count with all cause mortality and cardiovascular mortality in hypertensive us adults a cohort study from nhanes 2005 2006
topic Hypertension
Daily step count
Mortality
NHANES
url https://doi.org/10.1186/s12889-024-21216-y
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