Gut microbiome related to metabolic diseases after moderate-to-vigorous intensity exercise
Background/Objectives: The purpose of this study is to investigate changes in gut microbiota related to metabolic diseases after moderate and high-intensity exercise. A total of 24 participants were divided into three groups: Non-Exercise Group (NEG, n = 8, 28.6 ± 5.3 years, 176.0 ± 7.8 cm, 81.3 ± 1...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-10-01
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| Series: | Journal of Exercise Science & Fitness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1728869X2400056X |
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| author | Somi Yun Yongsuk Seo Yunbin Lee Dae Taek Lee |
| author_facet | Somi Yun Yongsuk Seo Yunbin Lee Dae Taek Lee |
| author_sort | Somi Yun |
| collection | DOAJ |
| description | Background/Objectives: The purpose of this study is to investigate changes in gut microbiota related to metabolic diseases after moderate and high-intensity exercise. A total of 24 participants were divided into three groups: Non-Exercise Group (NEG, n = 8, 28.6 ± 5.3 years, 176.0 ± 7.8 cm, 81.3 ± 14.6 kg), Moderate Intensity Exercise Group (MIEG, n = 8, 26.5 ± 3.3 years, 176.9 ± 5.0 cm, 75.4 ± 9.5 kg), and Vigorous Intensity Exercise Group (VIEG, n = 8, 30.6 ± 5.9 years, 174.2 ± 3.5 cm, 77.8 ± 12.2 kg). Methods: The participants were selected by assessing physical activity, gut health status, presence of diseases, recent disease diagnoses, and dietary disorders. Those who reported any presence disease or recent disease diagnosis were excluded from the current study. Stool samples were collected after a 10-h fast for gut microbiome analysis. MIEG participants trained at 40–59 % heart rate reserve (HRR) for at least 150 min per week, while VIEG participants trained at ≥ 60 % HRR for at least 90 min per week. After 4 weeks, all participants provided stool samples for gut microbiome analysis.Data analysis was conducted using the Wilcoxon test, with statistical significance set at ≤ 0.05. Results: The results indicated an increase in Prevotella in MIEG, while Veillonella, Dorea_formicigenerans, and Dorea_longicatena exhibited a decrease (p < 0.05). In VIEG, there was an increase in Bacteroides, Butyricimonas, Odoribacter, and Alistipes (p < 0.05). Conclusion: These modified microbial groups were associated with factors related to metabolic diseases, including inflammatory bowel disease, obesity, colorectal cancer, diabetes, hypertension, metabolic liver diseases, and ischemic heart diseases. Additional research is essential to delve into the relationship between exercise and these alterations in the microbiome. |
| format | Article |
| id | doaj-art-c03d77d3b4ab4984bfe6630dc48274c8 |
| institution | Kabale University |
| issn | 1728-869X |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Exercise Science & Fitness |
| spelling | doaj-art-c03d77d3b4ab4984bfe6630dc48274c82024-12-13T10:56:33ZengElsevierJournal of Exercise Science & Fitness1728-869X2024-10-01224375382Gut microbiome related to metabolic diseases after moderate-to-vigorous intensity exerciseSomi Yun0Yongsuk Seo1Yunbin Lee2Dae Taek Lee3Exercise Physiology Laboratory, Kookmin University, Seoul, Republic of KoreaExercise Physiology Laboratory, Kookmin University, Seoul, Republic of KoreaExercise Physiology Laboratory, Kookmin University, Seoul, Republic of KoreaCorresponding author.; Exercise Physiology Laboratory, Kookmin University, Seoul, Republic of KoreaBackground/Objectives: The purpose of this study is to investigate changes in gut microbiota related to metabolic diseases after moderate and high-intensity exercise. A total of 24 participants were divided into three groups: Non-Exercise Group (NEG, n = 8, 28.6 ± 5.3 years, 176.0 ± 7.8 cm, 81.3 ± 14.6 kg), Moderate Intensity Exercise Group (MIEG, n = 8, 26.5 ± 3.3 years, 176.9 ± 5.0 cm, 75.4 ± 9.5 kg), and Vigorous Intensity Exercise Group (VIEG, n = 8, 30.6 ± 5.9 years, 174.2 ± 3.5 cm, 77.8 ± 12.2 kg). Methods: The participants were selected by assessing physical activity, gut health status, presence of diseases, recent disease diagnoses, and dietary disorders. Those who reported any presence disease or recent disease diagnosis were excluded from the current study. Stool samples were collected after a 10-h fast for gut microbiome analysis. MIEG participants trained at 40–59 % heart rate reserve (HRR) for at least 150 min per week, while VIEG participants trained at ≥ 60 % HRR for at least 90 min per week. After 4 weeks, all participants provided stool samples for gut microbiome analysis.Data analysis was conducted using the Wilcoxon test, with statistical significance set at ≤ 0.05. Results: The results indicated an increase in Prevotella in MIEG, while Veillonella, Dorea_formicigenerans, and Dorea_longicatena exhibited a decrease (p < 0.05). In VIEG, there was an increase in Bacteroides, Butyricimonas, Odoribacter, and Alistipes (p < 0.05). Conclusion: These modified microbial groups were associated with factors related to metabolic diseases, including inflammatory bowel disease, obesity, colorectal cancer, diabetes, hypertension, metabolic liver diseases, and ischemic heart diseases. Additional research is essential to delve into the relationship between exercise and these alterations in the microbiome.http://www.sciencedirect.com/science/article/pii/S1728869X2400056XMetabolic diseaseExercise intensityMicrobiomeIntestinal environment |
| spellingShingle | Somi Yun Yongsuk Seo Yunbin Lee Dae Taek Lee Gut microbiome related to metabolic diseases after moderate-to-vigorous intensity exercise Journal of Exercise Science & Fitness Metabolic disease Exercise intensity Microbiome Intestinal environment |
| title | Gut microbiome related to metabolic diseases after moderate-to-vigorous intensity exercise |
| title_full | Gut microbiome related to metabolic diseases after moderate-to-vigorous intensity exercise |
| title_fullStr | Gut microbiome related to metabolic diseases after moderate-to-vigorous intensity exercise |
| title_full_unstemmed | Gut microbiome related to metabolic diseases after moderate-to-vigorous intensity exercise |
| title_short | Gut microbiome related to metabolic diseases after moderate-to-vigorous intensity exercise |
| title_sort | gut microbiome related to metabolic diseases after moderate to vigorous intensity exercise |
| topic | Metabolic disease Exercise intensity Microbiome Intestinal environment |
| url | http://www.sciencedirect.com/science/article/pii/S1728869X2400056X |
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