Skeletal Muscle Mass, Muscle Strength, and Quality of Life in Adult Patients with Familial Mediterranean Fever: A Comparative Study with Healthy Controls
Aim: This study (1) compared skeletal muscle mass (SMM) and muscle strength in familial Mediterranean fever (FMF) patients with those of healthy controls (HCs) and (2) investigated the association of SMM and muscle strength with disease severity and quality of life (QOL). Materials and Methods: This...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
2023-10-01
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| Series: | Genel Tıp Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/3175920 |
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| author | Enes Veziroğlu Taha Furkan Çakır Abdurrahman Soner Şenel Melih Kızıltepe Emel Oğuz Kökoğlu Hasan Kara Sinem Kübra Konca Rıdvan Yıldızhan İsa Cüce |
| author_facet | Enes Veziroğlu Taha Furkan Çakır Abdurrahman Soner Şenel Melih Kızıltepe Emel Oğuz Kökoğlu Hasan Kara Sinem Kübra Konca Rıdvan Yıldızhan İsa Cüce |
| author_sort | Enes Veziroğlu |
| collection | DOAJ |
| description | Aim: This study (1) compared skeletal muscle mass (SMM) and muscle strength in familial Mediterranean fever (FMF) patients with those of healthy controls (HCs) and (2) investigated the association of SMM and muscle strength with disease severity and quality of life (QOL).
Materials and Methods: This study included 31 FMF patients and 30 matched HCs. Disease severity was evaluated using the International Severity Scoring System for FMF (ISSF). Body composition parameters were measured using a bioelectrical impedance analysis. Grip and pinch strengths were calculated for muscle strength. Health status was assessed with Short Form 36 (SF-36).
Results: The all-body composition parameters of the FMF patients, including SMM, were similar to those of the HCs, with significantly lower grip and pinch strengths. All SF-36 scores of the FMF patients were significantly lower than those of the HCs. Positive correlations were observed between muscle-related indices and pinch strength for some SF-36 domains.
Conclusion: Muscle- or fat-related indices were similar among adult patients with FMF and the HCs. In contrast, patients with FMF had a poorer health-related QOL and lower grip and pinch strengths than the HCs. Further studies are needed to determine the clinical significance of these correlations in patients with FMF. |
| format | Article |
| id | doaj-art-c01a70f98fd94fbf93a76ed841748cfb |
| institution | Kabale University |
| issn | 2602-3741 |
| language | English |
| publishDate | 2023-10-01 |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Genel Tıp Dergisi |
| spelling | doaj-art-c01a70f98fd94fbf93a76ed841748cfb2025-01-03T00:46:52ZengSelcuk University PressGenel Tıp Dergisi2602-37412023-10-0133553654010.54005/geneltip.1306834154Skeletal Muscle Mass, Muscle Strength, and Quality of Life in Adult Patients with Familial Mediterranean Fever: A Comparative Study with Healthy ControlsEnes Veziroğlu0Taha Furkan Çakır1Abdurrahman Soner Şenel2Melih Kızıltepe3Emel Oğuz Kökoğlu4Hasan Kara5Sinem Kübra Konca6Rıdvan Yıldızhan7İsa Cüce8Nevşehir Devlet HastanesiERCİYES ÜNİVERSİTESİ, TIP FAKÜLTESİ, TIP PR.ERCİYES ÜNİVERSİTESİ, TIP FAKÜLTESİERCİYES ÜNİVERSİTESİ, TIP FAKÜLTESİERCİYES ÜNİVERSİTESİ, TIP FAKÜLTESİERCİYES ÜNİVERSİTESİ, TIP FAKÜLTESİBünyan Devlet HastanesiZile Devlet HastanesiERCİYES ÜNİVERSİTESİ, TIP FAKÜLTESİAim: This study (1) compared skeletal muscle mass (SMM) and muscle strength in familial Mediterranean fever (FMF) patients with those of healthy controls (HCs) and (2) investigated the association of SMM and muscle strength with disease severity and quality of life (QOL). Materials and Methods: This study included 31 FMF patients and 30 matched HCs. Disease severity was evaluated using the International Severity Scoring System for FMF (ISSF). Body composition parameters were measured using a bioelectrical impedance analysis. Grip and pinch strengths were calculated for muscle strength. Health status was assessed with Short Form 36 (SF-36). Results: The all-body composition parameters of the FMF patients, including SMM, were similar to those of the HCs, with significantly lower grip and pinch strengths. All SF-36 scores of the FMF patients were significantly lower than those of the HCs. Positive correlations were observed between muscle-related indices and pinch strength for some SF-36 domains. Conclusion: Muscle- or fat-related indices were similar among adult patients with FMF and the HCs. In contrast, patients with FMF had a poorer health-related QOL and lower grip and pinch strengths than the HCs. Further studies are needed to determine the clinical significance of these correlations in patients with FMF.https://dergipark.org.tr/tr/download/article-file/3175920familial mediterranean feverskeletal musclemuscle strengthquality of lifeailevi akdeniz ateşiiskelet kasıkas kuvvetiyaşam kalitesi |
| spellingShingle | Enes Veziroğlu Taha Furkan Çakır Abdurrahman Soner Şenel Melih Kızıltepe Emel Oğuz Kökoğlu Hasan Kara Sinem Kübra Konca Rıdvan Yıldızhan İsa Cüce Skeletal Muscle Mass, Muscle Strength, and Quality of Life in Adult Patients with Familial Mediterranean Fever: A Comparative Study with Healthy Controls Genel Tıp Dergisi familial mediterranean fever skeletal muscle muscle strength quality of life ailevi akdeniz ateşi iskelet kası kas kuvveti yaşam kalitesi |
| title | Skeletal Muscle Mass, Muscle Strength, and Quality of Life in Adult Patients with Familial Mediterranean Fever: A Comparative Study with Healthy Controls |
| title_full | Skeletal Muscle Mass, Muscle Strength, and Quality of Life in Adult Patients with Familial Mediterranean Fever: A Comparative Study with Healthy Controls |
| title_fullStr | Skeletal Muscle Mass, Muscle Strength, and Quality of Life in Adult Patients with Familial Mediterranean Fever: A Comparative Study with Healthy Controls |
| title_full_unstemmed | Skeletal Muscle Mass, Muscle Strength, and Quality of Life in Adult Patients with Familial Mediterranean Fever: A Comparative Study with Healthy Controls |
| title_short | Skeletal Muscle Mass, Muscle Strength, and Quality of Life in Adult Patients with Familial Mediterranean Fever: A Comparative Study with Healthy Controls |
| title_sort | skeletal muscle mass muscle strength and quality of life in adult patients with familial mediterranean fever a comparative study with healthy controls |
| topic | familial mediterranean fever skeletal muscle muscle strength quality of life ailevi akdeniz ateşi iskelet kası kas kuvveti yaşam kalitesi |
| url | https://dergipark.org.tr/tr/download/article-file/3175920 |
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