Biogenic Ag-ZnO nanoparticles synthesized via Andrographis macrobotrys Nees: A dual role in biomedical applications and methylene blue dye degradation

Biogenic Ag-ZnO nanoparticles synthesized via Andrographis macrobotrys Nees: A dual role in biomedical applications and methylene blue dye degradation

This study uses aqueous leaf extracts of Andrographis macrobotrys to create Ag-ZnO nanoparticles in a low-toxic, environmentally benign manner. Numerous analytical techniques, including as Ultra Violet-Vis spectroscopy, X-Ray Diffraction, Fourier Transform Infra-red Spectrum, Scanning Electron Micro...

Full description

Saved in:
Bibliographic Details
Main Authors: Sivakumar Saipraba, Raji Meena, Chinnasamy Ragavendran, Mansour K. Gatasheh, Anis Ahmed, Subban Murugesan
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Next Materials
Subjects:
Ag-doped ZnO nanoparticles
Cytotoxicity
Anti-inflammatory
Photocatalytic degradation
Online Access:http://www.sciencedirect.com/science/article/pii/S2949822825005489
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study uses aqueous leaf extracts of Andrographis macrobotrys to create Ag-ZnO nanoparticles in a low-toxic, environmentally benign manner. Numerous analytical techniques, including as Ultra Violet-Vis spectroscopy, X-Ray Diffraction, Fourier Transform Infra-red Spectrum, Scanning Electron Microscopy-Energy Dispersive X-ray, Transmission Electron Microscopy, and X-Ray Photoelectron Spectroscopy, are used on the resultant sample. Ag-ZnO nanoparticles had stronger antibacterial activity against four clinical pathogens, including K. pneumoniae and B. subtilis. The DPPH and ABTS assays were used to evaluate the antioxidant capacity, and the results showed maximal inhibitory concentrations (IC50) of 85.67 and 93.78 µg/mL, respectively. The A549 cell line's cytotoxicity was assessed using an MTT test, which yielded an IC50 value of 44.09 µg/mL. By using IC50 values of 227.95 and 224.15 µg/mL, respectively, the anti-inflammatory analysis validated the nanoparticles' therapeutic potential. The reaction combinations combining MB-Ag-ZnO nanoparticles demonstrated the greatest reduction in MB, with a 99 % drop, and were shown to be the most effective photocatalyst for dye degradation in the presence of direct sunlight.
ISSN:2949-8228

Similar Items