Filaggrin and Atopic Dermatitis: Clinical and Pathogenetic Parallels and Therapeutic Possibilities

Filaggrin and Atopic Dermatitis: Clinical and Pathogenetic Parallels and Therapeutic Possibilities

Atopic dermatitis (AtD) is multifactorial inflammatory skin disease, one of the aspects of its pathogenesis is epidermal barrier dysfunction. Early development of AtD is associated with filaggrin dysfunction. Filaggrin is a protein involved in aggregation of keratin filaments in the upper layers of...

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Bibliographic Details
Main Authors: Nikolay N. Murashkin, Roman A. Ivanov, Eduard T. Ambarchian, Roman V. Epishev, Alexander I. Materikin, Leonid A. Opryatin, Alena A. Savelova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2021-11-01
Series:Вопросы современной педиатрии
Subjects:
atopic dermatitis
filaggrin
emollient
filagrinol
epidermal barrier
corneal layer
ceramides
Online Access:https://vsp.spr-journal.ru/jour/article/view/2749
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