Oral cancer: Recent breakthroughs in pathology and therapeutic approaches
Oral cancer, primarily oral squamous cell carcinoma (OSCC), continues to be a major global health challenge. Despite improvements in early detection and treatment, the prognosis for patients, particularly those diagnosed at advanced stages, remains unfavorable. However, recent progress in understand...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Oral Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024005247 |
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| _version_ | 1846139871555485696 |
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| author | Surekha Ramachandran |
| author_facet | Surekha Ramachandran |
| author_sort | Surekha Ramachandran |
| collection | DOAJ |
| description | Oral cancer, primarily oral squamous cell carcinoma (OSCC), continues to be a major global health challenge. Despite improvements in early detection and treatment, the prognosis for patients, particularly those diagnosed at advanced stages, remains unfavorable. However, recent progress in understanding the molecular mechanisms of oral carcinogenesis and the development of innovative treatment approaches offer new hope for enhancing patient outcomes. This review highlights the latest discoveries in oral cancer pathology, key molecular drivers of disease progression, early detection strategies, and cutting-edge treatment options, including immunotherapy and targeted treatments. Additionally, it explores next-generation treatments incorporating artificial intelligence and machine learning. |
| format | Article |
| id | doaj-art-bfba2e1e05cd467291e9f7dc6fabe9e7 |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-bfba2e1e05cd467291e9f7dc6fabe9e72024-12-06T05:15:24ZengElsevierOral Oncology Reports2772-90602024-12-0112100678Oral cancer: Recent breakthroughs in pathology and therapeutic approachesSurekha Ramachandran0Department of Biochemistry, SRM Dental College, Bharathi Salai, Ramapuram, Chennai, 600 089, Tamil Nadu, IndiaOral cancer, primarily oral squamous cell carcinoma (OSCC), continues to be a major global health challenge. Despite improvements in early detection and treatment, the prognosis for patients, particularly those diagnosed at advanced stages, remains unfavorable. However, recent progress in understanding the molecular mechanisms of oral carcinogenesis and the development of innovative treatment approaches offer new hope for enhancing patient outcomes. This review highlights the latest discoveries in oral cancer pathology, key molecular drivers of disease progression, early detection strategies, and cutting-edge treatment options, including immunotherapy and targeted treatments. Additionally, it explores next-generation treatments incorporating artificial intelligence and machine learning.http://www.sciencedirect.com/science/article/pii/S2772906024005247Oral squamous cell carcinomaTargeted therapyImmunotherapyMolecular profilingArtificial intelligenceNanotechnology |
| spellingShingle | Surekha Ramachandran Oral cancer: Recent breakthroughs in pathology and therapeutic approaches Oral Oncology Reports Oral squamous cell carcinoma Targeted therapy Immunotherapy Molecular profiling Artificial intelligence Nanotechnology |
| title | Oral cancer: Recent breakthroughs in pathology and therapeutic approaches |
| title_full | Oral cancer: Recent breakthroughs in pathology and therapeutic approaches |
| title_fullStr | Oral cancer: Recent breakthroughs in pathology and therapeutic approaches |
| title_full_unstemmed | Oral cancer: Recent breakthroughs in pathology and therapeutic approaches |
| title_short | Oral cancer: Recent breakthroughs in pathology and therapeutic approaches |
| title_sort | oral cancer recent breakthroughs in pathology and therapeutic approaches |
| topic | Oral squamous cell carcinoma Targeted therapy Immunotherapy Molecular profiling Artificial intelligence Nanotechnology |
| url | http://www.sciencedirect.com/science/article/pii/S2772906024005247 |
| work_keys_str_mv | AT surekharamachandran oralcancerrecentbreakthroughsinpathologyandtherapeuticapproaches |