Identifiability of phenotypic adaptation from low-cell-count experiments and a stochastic model.
Phenotypic plasticity contributes significantly to treatment failure in many cancers. Despite the increased prevalence of experimental studies that interrogate this phenomenon, there remains a lack of applicable quantitative tools to characterise data, and importantly to distinguish between resistan...
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| Main Authors: | Alexander P Browning, Rebecca M Crossley, Chiara Villa, Philip K Maini, Adrianne L Jenner, Tyler Cassidy, Sara Hamis |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-06-01
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| Series: | PLoS Computational Biology |
| Online Access: | https://doi.org/10.1371/journal.pcbi.1013202 |
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