The mesenteric adipokine SFRP5 alleviated intestinal epithelial apoptosis improving barrier dysfunction in Crohn's disease

The mesenteric adipokine SFRP5 alleviated intestinal epithelial apoptosis improving barrier dysfunction in Crohn's disease

Summary: The hypertrophic mesenteric adipose tissue (htMAT) of Crohn disease (CD) participates in inflammation through the expression of adipokines, but the exact mechanism of this action in the intestine is unknown. Here, we analyzed the expression of secreted frizzled-related protein 5 (SFRP5), an...

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Bibliographic Details
Main Authors: Xiaofeng Zhang, Lugen Zuo, Xue Song, Wenjing Zhang, Zi Yang, Zhiyuan Wang, Yibing Guo, Sitang Ge, Lian Wang, Yueyue Wang, Zhijun Geng, Jing Li, Jianguo Hu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224027445
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