The Case of Сushing Syndrome in a Child of 15 Years after Prolonged Endonasal Use of Dexamethasone

Abstract. The article describes the case of drug Cushing syndrome as a result of prolonged (for 10 months) endonasal use of dexamethasone and oxymetazoline mixture, which was prepared by the patient’s mother. Medical control was absent. The content of dexamethasone in the vial and the concentration...

Full description

Saved in:
Bibliographic Details
Main Authors: S. S. Postnikov, M. E. Karmanov, E. V. Kuvaldina, A. Z. Gadzhieva, M. N. Kostyleva, A. N. Gratsianskaya, A. E. Ermilin
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2018-12-01
Series:Безопасность и риск фармакотерапии
Subjects:
Online Access:https://www.risksafety.ru/jour/article/view/131
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849252353446772736
author S. S. Postnikov
M. E. Karmanov
E. V. Kuvaldina
A. Z. Gadzhieva
M. N. Kostyleva
A. N. Gratsianskaya
A. E. Ermilin
author_facet S. S. Postnikov
M. E. Karmanov
E. V. Kuvaldina
A. Z. Gadzhieva
M. N. Kostyleva
A. N. Gratsianskaya
A. E. Ermilin
author_sort S. S. Postnikov
collection DOAJ
description Abstract. The article describes the case of drug Cushing syndrome as a result of prolonged (for 10 months) endonasal use of dexamethasone and oxymetazoline mixture, which was prepared by the patient’s mother. Medical control was absent. The content of dexamethasone in the vial and the concentration of oxymetazoline was not known. During the examination, in addition to Cushing syndrome, an atrophy of the nasal mucosa as a second side effect was revealed. Thus, in the above case, there were two complications of incorrect using of drugs — local and systemic.
format Article
id doaj-art-bf6963a1b70f4e98bd7e560c8ccd8f84
institution Kabale University
issn 2312-7821
2619-1164
language Russian
publishDate 2018-12-01
publisher Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»
record_format Article
series Безопасность и риск фармакотерапии
spelling doaj-art-bf6963a1b70f4e98bd7e560c8ccd8f842025-08-20T03:56:40ZrusMinistry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»Безопасность и риск фармакотерапии2312-78212619-11642018-12-016418719010.30895/2312-7821-2018-6-4-187-190120The Case of Сushing Syndrome in a Child of 15 Years after Prolonged Endonasal Use of DexamethasoneS. S. Postnikov0M. E. Karmanov1E. V. Kuvaldina2A. Z. Gadzhieva3M. N. Kostyleva4A. N. Gratsianskaya5A. E. Ermilin6Pirogov Russian National Research Medical University; Russian Children’s Clinical Hospital of the Pirogov Russian National Research Medical University, MoscowRussian Children’s Clinical Hospital of the Pirogov Russian National Research Medical University, MoscowRussian Children’s Clinical Hospital of the Pirogov Russian National Research Medical University, MoscowPirogov Russian National Research Medical University; Russian Children’s Clinical Hospital of the Pirogov Russian National Research Medical University, MoscowPirogov Russian National Research Medical University; Russian Children’s Clinical Hospital of the Pirogov Russian National Research Medical University, MoscowPirogov Russian National Research Medical University, MoscowPirogov Russian National Research Medical University; Russian Children’s Clinical Hospital of the Pirogov Russian National Research Medical University, MoscowAbstract. The article describes the case of drug Cushing syndrome as a result of prolonged (for 10 months) endonasal use of dexamethasone and oxymetazoline mixture, which was prepared by the patient’s mother. Medical control was absent. The content of dexamethasone in the vial and the concentration of oxymetazoline was not known. During the examination, in addition to Cushing syndrome, an atrophy of the nasal mucosa as a second side effect was revealed. Thus, in the above case, there were two complications of incorrect using of drugs — local and systemic.https://www.risksafety.ru/jour/article/view/131nasal dropsdexamethasoneoxymetazolinecushing syndromeatrophy of the nasal mucosachildren
spellingShingle S. S. Postnikov
M. E. Karmanov
E. V. Kuvaldina
A. Z. Gadzhieva
M. N. Kostyleva
A. N. Gratsianskaya
A. E. Ermilin
The Case of Сushing Syndrome in a Child of 15 Years after Prolonged Endonasal Use of Dexamethasone
Безопасность и риск фармакотерапии
nasal drops
dexamethasone
oxymetazoline
cushing syndrome
atrophy of the nasal mucosa
children
title The Case of Сushing Syndrome in a Child of 15 Years after Prolonged Endonasal Use of Dexamethasone
title_full The Case of Сushing Syndrome in a Child of 15 Years after Prolonged Endonasal Use of Dexamethasone
title_fullStr The Case of Сushing Syndrome in a Child of 15 Years after Prolonged Endonasal Use of Dexamethasone
title_full_unstemmed The Case of Сushing Syndrome in a Child of 15 Years after Prolonged Endonasal Use of Dexamethasone
title_short The Case of Сushing Syndrome in a Child of 15 Years after Prolonged Endonasal Use of Dexamethasone
title_sort case of сushing syndrome in a child of 15 years after prolonged endonasal use of dexamethasone
topic nasal drops
dexamethasone
oxymetazoline
cushing syndrome
atrophy of the nasal mucosa
children
url https://www.risksafety.ru/jour/article/view/131
work_keys_str_mv AT sspostnikov thecaseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT mekarmanov thecaseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT evkuvaldina thecaseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT azgadzhieva thecaseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT mnkostyleva thecaseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT angratsianskaya thecaseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT aeermilin thecaseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT sspostnikov caseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT mekarmanov caseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT evkuvaldina caseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT azgadzhieva caseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT mnkostyleva caseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT angratsianskaya caseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone
AT aeermilin caseofsushingsyndromeinachildof15yearsafterprolongedendonasaluseofdexamethasone