The effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity
<b>Aim: </b>The aim of this study was to determine the effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity.<p> <b>Materials and Methods:</b> Adult male Wistar-Albino rats (n = 30) were used and divided into four...
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=1244 |
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| author | İhsan Kısadere Nurcan Dönmez |
| author_facet | İhsan Kısadere Nurcan Dönmez |
| author_sort | İhsan Kısadere |
| collection | DOAJ |
| description | <b>Aim: </b>The aim of this study was to determine the effects of quercetin
on antioxidant system and some blood parameters in
rats exposed to acute cadmium toxicity.<p>
<b>Materials and Methods:</b> Adult male Wistar-Albino rats (n
= 30) were used and divided into four groups as Control (C, n
= 6), Cadmium (Cd, n = 8), Quercetin (Q, n = 8) and Cadmium
+ Quercetin (Cd + Q, n = 8). Cadmium chloride (CdCl2, 4 mg/
kg daily, s.c) were administrated to Cd and Cd+Q groups, and
Quercetin (Q, 50 mg/kg daily, i.p) were given to Q and Cd + Q
groups for 3 days, respectively. Control group was not recieved
any treatment. Blood samples were collected from all animals
at fourth day after treatments.<p>
<b>Results:</b> The levels of serum SOD, MDA, GSH, catalase, and
plasma ALT, AST, GGT, total protein, albumin were detected.
Although, serum MDA levels were found higher (P< 0.05) in
Cd than the other groups, it was similiar in Q and C groups.
ALT, AST and GGT enzyme levels were observed higher in Cd
than C and Q groups (P< 0.05).<p>
<b>Conclusion:</b> Negative effects of acute cadmium toxicity on
antioxidan system and some hematological parameters were
ameliorated with quercetin treatment in rats. |
| format | Article |
| id | doaj-art-bf62d7e2a15a403391709d9bec23675c |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-bf62d7e2a15a403391709d9bec23675c2025-01-02T22:36:19ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-195335266701244The effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicityİhsan Kısadere0Nurcan Dönmez1Balıkesir University, Faculty of Veterinary Medicine, Department of Physiology, Balıkesir, TurkeySelcuk University, Faculty of Veterinary Medicine, Department of Physiology, Konya, Turkey<b>Aim: </b>The aim of this study was to determine the effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity.<p> <b>Materials and Methods:</b> Adult male Wistar-Albino rats (n = 30) were used and divided into four groups as Control (C, n = 6), Cadmium (Cd, n = 8), Quercetin (Q, n = 8) and Cadmium + Quercetin (Cd + Q, n = 8). Cadmium chloride (CdCl2, 4 mg/ kg daily, s.c) were administrated to Cd and Cd+Q groups, and Quercetin (Q, 50 mg/kg daily, i.p) were given to Q and Cd + Q groups for 3 days, respectively. Control group was not recieved any treatment. Blood samples were collected from all animals at fourth day after treatments.<p> <b>Results:</b> The levels of serum SOD, MDA, GSH, catalase, and plasma ALT, AST, GGT, total protein, albumin were detected. Although, serum MDA levels were found higher (P< 0.05) in Cd than the other groups, it was similiar in Q and C groups. ALT, AST and GGT enzyme levels were observed higher in Cd than C and Q groups (P< 0.05).<p> <b>Conclusion:</b> Negative effects of acute cadmium toxicity on antioxidan system and some hematological parameters were ameliorated with quercetin treatment in rats.http://eurasianjvetsci.org/pdf.php3?id=1244antioxidantsblood parameterscadmiumquercetinrats |
| spellingShingle | İhsan Kısadere Nurcan Dönmez The effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity Eurasian Journal of Veterinary Sciences antioxidants blood parameters cadmium quercetin rats |
| title | The effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity |
| title_full | The effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity |
| title_fullStr | The effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity |
| title_full_unstemmed | The effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity |
| title_short | The effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity |
| title_sort | effects of quercetin on antioxidant system and some blood parameters in rats exposed to acute cadmium toxicity |
| topic | antioxidants blood parameters cadmium quercetin rats |
| url | http://eurasianjvetsci.org/pdf.php3?id=1244 |
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