Study protocol of the ASTOP trial: A multicenter, randomized, double-blind, placebo-controlled trial of presurgical aspirin administration for the prevention of thromboembolic complications of coil embolization for ruptured aneurysms.

Study protocol of the ASTOP trial: A multicenter, randomized, double-blind, placebo-controlled trial of presurgical aspirin administration for the prevention of thromboembolic complications of coil embolization for ruptured aneurysms.

<h4>Rationale</h4>Thromboembolism is a serious complication of endovascular treatment for ruptured cerebral aneurysms. The administration of antiplatelet agents before endovascular treatment for ruptured cerebral aneurysms may reduce the risk of thromboembolic complications.<h4>Aim...

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Main Authors: Sakyo Hirai, Kyohei Fujita, Shoko Fujii, Satoru Takahashi, Keigo Shigeta, Jun Karakama, Yukiko Enomoto, Yohei Sato, Masataka Yoshimura, Shin Hirota, Tatsuya Mizoue, Yoshikazu Yoshino, Yoshihisa Kawano, Toshihiro Yamamura, Shinya Kohyama, Masaru Hirohata, Shinichi Yoshimura, Yosuke Ishii, Toshihiro Yamauchi, Naoki Taira, Yoshiki Obata, Makoto Sakamoto, Masato Inoue, Motoshige Yamashina, So Tokunaga, Toshio Higashi, Kana Sawada, Hidetoshi Mochida, Keisuke Ido, Masataka Takeuchi, Tomoji Takigawa, Yasushi Takagi, Masafumi Morimoto, Masataka Nanto, Kazunori Miki, Kouichi Misaki, Koichi Arimura, Yoshiki Hanaoka, Mutsuya Hara, Shoko Hara, Kota Yokoyama, Jun Ooyama, Ryoichi Hanazawa, Hiroyuki Sato, Akihiro Hirakawa, Megumi Ishiguro, Shigeru Nemoto, Kazutaka Sumita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0310906
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