Ambient ozone and mortality from respiratory diseases: A nationwide analysis in China

Background: Although the health impacts of ambient ozone (O3) have been widely assessed, studies simultaneously investigating the acute and chronic effects of O3 on mortality from respiratory diseases (RESP) are scarce. Methods: We extracted personal information of all recorded deaths from RESP thro...

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Main Authors: Weiling Tang, Min Yu, Guoxia Bai, Chunliang Zhou, Ruilin Meng, Biao Huang, Weiwei Gong, Zhulin Hou, Jianxiong Hu, Guanhao He, Lifeng Lin, Yanfang Guo, Juanjuan Zhang, Qijiong Zhu, Zhiqing Chen, Siwen Yu, Yuan Zheng, Yayi Li, Jiahong Xu, Xiaofeng Liang, Wenjun Ma, Tao Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-01-01
Series:Global Transitions
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589791824000057
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author Weiling Tang
Min Yu
Guoxia Bai
Chunliang Zhou
Ruilin Meng
Biao Huang
Weiwei Gong
Zhulin Hou
Jianxiong Hu
Guanhao He
Lifeng Lin
Yanfang Guo
Juanjuan Zhang
Qijiong Zhu
Zhiqing Chen
Siwen Yu
Yuan Zheng
Yayi Li
Jiahong Xu
Xiaofeng Liang
Wenjun Ma
Tao Liu
author_facet Weiling Tang
Min Yu
Guoxia Bai
Chunliang Zhou
Ruilin Meng
Biao Huang
Weiwei Gong
Zhulin Hou
Jianxiong Hu
Guanhao He
Lifeng Lin
Yanfang Guo
Juanjuan Zhang
Qijiong Zhu
Zhiqing Chen
Siwen Yu
Yuan Zheng
Yayi Li
Jiahong Xu
Xiaofeng Liang
Wenjun Ma
Tao Liu
author_sort Weiling Tang
collection DOAJ
description Background: Although the health impacts of ambient ozone (O3) have been widely assessed, studies simultaneously investigating the acute and chronic effects of O3 on mortality from respiratory diseases (RESP) are scarce. Methods: We extracted personal information of all recorded deaths from RESP throughout 2013–2018 in six provinces in China. The daily, seasonal, and annual mean air pollutant concentrations at the township/subdistrict level were estimated by a random forest model. The acute association between the maximum daily average 8h ozone (MDA8 O3) and RESP mortality was examined by a time-stratified case-crossover study design, and the chronic association was estimated by a difference-in-differences (DID) analysis approach. We also calculated the attributable fraction (AF) of RESP mortality attributable to MDA8 O3. Results: There were 1,034,226 RESP deaths included in this study. The excess risks (ERs) of overall RESP mortality for each 10 μg/m3 increase in short-term (lag03 days) and long-term (one-year average) exposure to MDA8 O3 were 0.38 % (95%CI: 0.26 %, 0.50 %) and 4.37 % (3.91 %, 4.84 %), respectively. The AFs of overall RESP mortality ascribed to short- and long-term MDA8 O3 exposures were 3.00 % (2.03 %, 3.95 %) and 29.45 % (26.86 %, 31.95 %), respectively. The average annual number of RESP deaths attributable to short-term MDA8 O3 exposure was 30,790 and 302,254 were attributable to long-term MDA8 O3 exposure across China during 2013–2018. Conclusion: Both short- and long-term exposure to ambient MDA8 O3 were positively associated with RESP mortality, and long-term exposure to MDA8 O3 may lead to a greater RESP mortality burden than short-term exposure to MDA8 O3.
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spelling doaj-art-bf073f4bf0a649f688429b81d5ba43082024-12-06T05:14:11ZengKeAi Communications Co., Ltd.Global Transitions2589-79182024-01-016113122Ambient ozone and mortality from respiratory diseases: A nationwide analysis in ChinaWeiling Tang0Min Yu1Guoxia Bai2Chunliang Zhou3Ruilin Meng4Biao Huang5Weiwei Gong6Zhulin Hou7Jianxiong Hu8Guanhao He9Lifeng Lin10Yanfang Guo11Juanjuan Zhang12Qijiong Zhu13Zhiqing Chen14Siwen Yu15Yuan Zheng16Yayi Li17Jiahong Xu18Xiaofeng Liang19Wenjun Ma20Tao Liu21Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, ChinaZhejiang Center for Disease Control and Prevention, Hangzhou, Zhejiang, 310051, ChinaInstitute of Non-communicable Diseases Prevention and Control, Tibet Center for Disease Control and Prevention, Lhasa, 850000, ChinaDepartment of Environment and Health, Hunan Provincial Center for Disease Control and Prevention, Changsha, 450001, ChinaGuangdong Provincial Center for Disease Control and Prevention, Guangzhou, 511430, ChinaHealth Hazard Factors Control Department, Jilin Provincial Center for Disease Control and Prevention, Changchun, 130062, ChinaZhejiang Center for Disease Control and Prevention, Hangzhou, Zhejiang, 310051, ChinaHealth Hazard Factors Control Department, Jilin Provincial Center for Disease Control and Prevention, Changchun, 130062, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, ChinaGuangdong Provincial Center for Disease Control and Prevention, Guangzhou, 511430, ChinaBao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, 518101, ChinaBao'an Center for Chronic Disease Control, Shenzhen, 518101, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, ChinaChina Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou, 510632, China; Corresponding author. Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, 510632, China; Corresponding author. Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, No.601 West, Huangpu Road, Tianhe District, Guangzhou, 510632, China.Background: Although the health impacts of ambient ozone (O3) have been widely assessed, studies simultaneously investigating the acute and chronic effects of O3 on mortality from respiratory diseases (RESP) are scarce. Methods: We extracted personal information of all recorded deaths from RESP throughout 2013–2018 in six provinces in China. The daily, seasonal, and annual mean air pollutant concentrations at the township/subdistrict level were estimated by a random forest model. The acute association between the maximum daily average 8h ozone (MDA8 O3) and RESP mortality was examined by a time-stratified case-crossover study design, and the chronic association was estimated by a difference-in-differences (DID) analysis approach. We also calculated the attributable fraction (AF) of RESP mortality attributable to MDA8 O3. Results: There were 1,034,226 RESP deaths included in this study. The excess risks (ERs) of overall RESP mortality for each 10 μg/m3 increase in short-term (lag03 days) and long-term (one-year average) exposure to MDA8 O3 were 0.38 % (95%CI: 0.26 %, 0.50 %) and 4.37 % (3.91 %, 4.84 %), respectively. The AFs of overall RESP mortality ascribed to short- and long-term MDA8 O3 exposures were 3.00 % (2.03 %, 3.95 %) and 29.45 % (26.86 %, 31.95 %), respectively. The average annual number of RESP deaths attributable to short-term MDA8 O3 exposure was 30,790 and 302,254 were attributable to long-term MDA8 O3 exposure across China during 2013–2018. Conclusion: Both short- and long-term exposure to ambient MDA8 O3 were positively associated with RESP mortality, and long-term exposure to MDA8 O3 may lead to a greater RESP mortality burden than short-term exposure to MDA8 O3.http://www.sciencedirect.com/science/article/pii/S2589791824000057Air pollutionAmbient ozoneRespiratory mortalityDisease burden
spellingShingle Weiling Tang
Min Yu
Guoxia Bai
Chunliang Zhou
Ruilin Meng
Biao Huang
Weiwei Gong
Zhulin Hou
Jianxiong Hu
Guanhao He
Lifeng Lin
Yanfang Guo
Juanjuan Zhang
Qijiong Zhu
Zhiqing Chen
Siwen Yu
Yuan Zheng
Yayi Li
Jiahong Xu
Xiaofeng Liang
Wenjun Ma
Tao Liu
Ambient ozone and mortality from respiratory diseases: A nationwide analysis in China
Global Transitions
Air pollution
Ambient ozone
Respiratory mortality
Disease burden
title Ambient ozone and mortality from respiratory diseases: A nationwide analysis in China
title_full Ambient ozone and mortality from respiratory diseases: A nationwide analysis in China
title_fullStr Ambient ozone and mortality from respiratory diseases: A nationwide analysis in China
title_full_unstemmed Ambient ozone and mortality from respiratory diseases: A nationwide analysis in China
title_short Ambient ozone and mortality from respiratory diseases: A nationwide analysis in China
title_sort ambient ozone and mortality from respiratory diseases a nationwide analysis in china
topic Air pollution
Ambient ozone
Respiratory mortality
Disease burden
url http://www.sciencedirect.com/science/article/pii/S2589791824000057
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