Gold Nanoparticle Inhibits the Tumor-Associated Macrophage M2 Polarization by Inhibiting m6A Methylation-Dependent ATG5/Autophagy in Prostate Cancer
Conclusion: The ATG5/autophagy pathway is inhibited by AuNP treatment in an METTL3/m6A-dependent manner. AuNPs inhibit the TAM M2 polarization in HSPC and CRPC by inhibiting ATG5/autophagy.
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.1155/ancp/6648632 |
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| _version_ | 1841545690317062144 |
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| author | Yuanyuan Hao Feng Duan Xianning Dong Ran Bi Yinzhe Wang Senqiang Zhu Jinghai Hu |
| author_facet | Yuanyuan Hao Feng Duan Xianning Dong Ran Bi Yinzhe Wang Senqiang Zhu Jinghai Hu |
| author_sort | Yuanyuan Hao |
| collection | DOAJ |
| description | Conclusion: The ATG5/autophagy pathway is inhibited by AuNP treatment in an METTL3/m6A-dependent manner. AuNPs inhibit the TAM M2 polarization in HSPC and CRPC by inhibiting ATG5/autophagy. |
| format | Article |
| id | doaj-art-bef56a0da37748a88768217433eb10b1 |
| institution | Kabale University |
| issn | 2210-7185 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-bef56a0da37748a88768217433eb10b12025-01-12T00:00:02ZengWileyAnalytical Cellular Pathology2210-71852025-01-01202510.1155/ancp/6648632Gold Nanoparticle Inhibits the Tumor-Associated Macrophage M2 Polarization by Inhibiting m6A Methylation-Dependent ATG5/Autophagy in Prostate CancerYuanyuan Hao0Feng Duan1Xianning Dong2Ran Bi3Yinzhe Wang4Senqiang Zhu5Jinghai Hu6Department of UrologyDepartment of OncologyDepartment of PathologyDepartment of UrologyDepartment of UrologyDepartment of UrologyDepartment of UrologyConclusion: The ATG5/autophagy pathway is inhibited by AuNP treatment in an METTL3/m6A-dependent manner. AuNPs inhibit the TAM M2 polarization in HSPC and CRPC by inhibiting ATG5/autophagy.http://dx.doi.org/10.1155/ancp/6648632 |
| spellingShingle | Yuanyuan Hao Feng Duan Xianning Dong Ran Bi Yinzhe Wang Senqiang Zhu Jinghai Hu Gold Nanoparticle Inhibits the Tumor-Associated Macrophage M2 Polarization by Inhibiting m6A Methylation-Dependent ATG5/Autophagy in Prostate Cancer Analytical Cellular Pathology |
| title | Gold Nanoparticle Inhibits the Tumor-Associated Macrophage M2 Polarization by Inhibiting m6A Methylation-Dependent ATG5/Autophagy in Prostate Cancer |
| title_full | Gold Nanoparticle Inhibits the Tumor-Associated Macrophage M2 Polarization by Inhibiting m6A Methylation-Dependent ATG5/Autophagy in Prostate Cancer |
| title_fullStr | Gold Nanoparticle Inhibits the Tumor-Associated Macrophage M2 Polarization by Inhibiting m6A Methylation-Dependent ATG5/Autophagy in Prostate Cancer |
| title_full_unstemmed | Gold Nanoparticle Inhibits the Tumor-Associated Macrophage M2 Polarization by Inhibiting m6A Methylation-Dependent ATG5/Autophagy in Prostate Cancer |
| title_short | Gold Nanoparticle Inhibits the Tumor-Associated Macrophage M2 Polarization by Inhibiting m6A Methylation-Dependent ATG5/Autophagy in Prostate Cancer |
| title_sort | gold nanoparticle inhibits the tumor associated macrophage m2 polarization by inhibiting m6a methylation dependent atg5 autophagy in prostate cancer |
| url | http://dx.doi.org/10.1155/ancp/6648632 |
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