The involvement of nicotinate and nicotinamide metabolism pathway in attenuating benzene-induced mouse hematotoxicity

The involvement of nicotinate and nicotinamide metabolism pathway in attenuating benzene-induced mouse hematotoxicity

Benzene exposure has been linked to various adverse health effects. However, the effective strategy for prevention or treatment of benzene-induced hematotoxicity remains unsolved. We previously administrated hepatocyte-specific deletion of Ppp2r1a gene (encoding PP2A Aα subunit) mice with benzene vi...

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Bibliographic Details
Main Authors: Rongfang Yang, Jiaxin Zhang, Xiumei Xing, Shiyuan Zhong, Wenxue Li, Lixian Wen, Yuwei Zhang, Hongwei Zhou, Shen Chen, Wen Chen, Yongmei Xiao, Liping Chen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Metabolomics
Transcriptomics
1-methylnicotinamide
Benzene
Hematotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324014647
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