Acute Stroke due to Vertebral Artery Dissection in Giant Cell Arteritis

The diagnosis of giant cell arteritis (GCA) when presenting with atypical features such as stroke is very challenging. Only 0.17% of first-ever strokes are caused by GCA, a life-threatening condition when left untreated. Very few cases have been reported on giant cell arteritis leading to acute stro...

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Main Authors: Marlene Marte Furment, Sandra Antigua Jimenez, Sangeetha Pabolu
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2021/5518541
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author Marlene Marte Furment
Sandra Antigua Jimenez
Sangeetha Pabolu
author_facet Marlene Marte Furment
Sandra Antigua Jimenez
Sangeetha Pabolu
author_sort Marlene Marte Furment
collection DOAJ
description The diagnosis of giant cell arteritis (GCA) when presenting with atypical features such as stroke is very challenging. Only 0.17% of first-ever strokes are caused by GCA, a life-threatening condition when left untreated. Very few cases have been reported on giant cell arteritis leading to acute stroke due to vertebral artery dissection. We present a case of a 76-year-old female with no medical history who presented with sudden onset right visual loss and left hemiparesis. She had been initially treated for acute stroke and upon further workup was found to have left vertebral artery dissection. She had erythrocyte sedimentation rate (ESR) of 71 mm/h, and bilateral temporal artery biopsy was consistent with giant cell arteritis. Patient received high doses of methylprednisolone which resolved her hemiparesis, but her vision loss did not improve. Stroke in the presence of significant involvement of vertebral arteries should raise suspicion of GCA especially if classic symptoms preceded stroke event. High clinical suspicion is required to prevent delay in diagnosis and treatment.
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spelling doaj-art-be8aa66771964aaf90457839a1533cad2025-02-03T05:47:39ZengWileyCase Reports in Rheumatology2090-68892090-68972021-01-01202110.1155/2021/55185415518541Acute Stroke due to Vertebral Artery Dissection in Giant Cell ArteritisMarlene Marte Furment0Sandra Antigua Jimenez1Sangeetha Pabolu2Internal Medicine Department, Saint Peter’s University Hospital/Rutgers Robert Wood Johnson Medical School Program, New Brunswick, NJ, USADepartment of Health Sciences, Instituto Tecnologico de Santo Domingo, Santo Domingo, Dominican RepublicRheumatology Department, Saint Peter’s University Hospital/Rutgers Robert Wood Johnson Medical School Program, New Brunswick, NJ, USAThe diagnosis of giant cell arteritis (GCA) when presenting with atypical features such as stroke is very challenging. Only 0.17% of first-ever strokes are caused by GCA, a life-threatening condition when left untreated. Very few cases have been reported on giant cell arteritis leading to acute stroke due to vertebral artery dissection. We present a case of a 76-year-old female with no medical history who presented with sudden onset right visual loss and left hemiparesis. She had been initially treated for acute stroke and upon further workup was found to have left vertebral artery dissection. She had erythrocyte sedimentation rate (ESR) of 71 mm/h, and bilateral temporal artery biopsy was consistent with giant cell arteritis. Patient received high doses of methylprednisolone which resolved her hemiparesis, but her vision loss did not improve. Stroke in the presence of significant involvement of vertebral arteries should raise suspicion of GCA especially if classic symptoms preceded stroke event. High clinical suspicion is required to prevent delay in diagnosis and treatment.http://dx.doi.org/10.1155/2021/5518541
spellingShingle Marlene Marte Furment
Sandra Antigua Jimenez
Sangeetha Pabolu
Acute Stroke due to Vertebral Artery Dissection in Giant Cell Arteritis
Case Reports in Rheumatology
title Acute Stroke due to Vertebral Artery Dissection in Giant Cell Arteritis
title_full Acute Stroke due to Vertebral Artery Dissection in Giant Cell Arteritis
title_fullStr Acute Stroke due to Vertebral Artery Dissection in Giant Cell Arteritis
title_full_unstemmed Acute Stroke due to Vertebral Artery Dissection in Giant Cell Arteritis
title_short Acute Stroke due to Vertebral Artery Dissection in Giant Cell Arteritis
title_sort acute stroke due to vertebral artery dissection in giant cell arteritis
url http://dx.doi.org/10.1155/2021/5518541
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