A retrospective study on the efficacy of integrating traditional Chinese medicine with Western medicine in the treatment of adult measles

Abstract Objective Measles is a highly contagious, potentially fatal disease, and using western medicine for treating this disease showed some limits including the long period of treatment and some side effects. Of note, traditional Chinese medicine (TCM) exhibited advantages of treating measles in...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaoyan Liu, Zhongying Bao, Shuhong Duan, Jing Sun, Jie Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Hereditas
Subjects:
Online Access:https://doi.org/10.1186/s41065-025-00518-0
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849332704988889088
author Xiaoyan Liu
Zhongying Bao
Shuhong Duan
Jing Sun
Jie Zhang
author_facet Xiaoyan Liu
Zhongying Bao
Shuhong Duan
Jing Sun
Jie Zhang
author_sort Xiaoyan Liu
collection DOAJ
description Abstract Objective Measles is a highly contagious, potentially fatal disease, and using western medicine for treating this disease showed some limits including the long period of treatment and some side effects. Of note, traditional Chinese medicine (TCM) exhibited advantages of treating measles in using alone or combing with western medication. However, little information on the clinical study on adjunctive efficacy of TCM on measles. Therefore, the objective of this study is to observe the adjunctive efficacy of TCM in the treatment of adult measles. Methods Ninety-one patients diagnosed with adult measles in our hospital were enrolled for this study. All of them underwent symptomatic treatment, nutritional support therapy, and ribavirin antiviral therapy. Loxoprofen was added to the treatment regime when the body temperature exceeded 38.5 °C. The patients were stratified into two groups based on the administration of TCM, comprising 49 individuals in the TCM group and 42 individuals in the control group. Patients in the TCM group voluntarily received the following TCM prescriptions: 15 g of Lonicerae Japonica, 15 g of Forsythiae Fructus, 15 g of Arnebiae Radix, 15 g of Cicadae Periostracum, 30 g of Phragmitis Rhizoma, 10 g of Anemarrhenae Rhizoma, 6 g of Glycyrrhizae Radix et Rhizoma and 30 g of Gypsum Fibrosum was administered to patients with high fever. Decoction: 1 dose daily for 5 days. The control group received treatment without the incorporation of TCM. Results In comparison to the control group, patients in the TCM group experienced a quicker resolution of clinical symptoms (P < 0.05) and a lower complication rate (P < 0.05). Conclusion The application of TCM in treating adult measles can shorten the duration of the disease, reduce the incidence of complications, and offers promise for wider clinical adoption and utilization.
format Article
id doaj-art-be79c6f2e08e46d1b5a8194227bea5f6
institution Kabale University
issn 1601-5223
language English
publishDate 2025-07-01
publisher BMC
record_format Article
series Hereditas
spelling doaj-art-be79c6f2e08e46d1b5a8194227bea5f62025-08-20T03:46:07ZengBMCHereditas1601-52232025-07-0116211710.1186/s41065-025-00518-0A retrospective study on the efficacy of integrating traditional Chinese medicine with Western medicine in the treatment of adult measlesXiaoyan Liu0Zhongying Bao1Shuhong Duan2Jing Sun3Jie Zhang4Department of Infectious Diseases, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Infectious Diseases, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Infectious Diseases, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Infectious Diseases, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Infectious Diseases, Beijing Shijitan Hospital, Capital Medical UniversityAbstract Objective Measles is a highly contagious, potentially fatal disease, and using western medicine for treating this disease showed some limits including the long period of treatment and some side effects. Of note, traditional Chinese medicine (TCM) exhibited advantages of treating measles in using alone or combing with western medication. However, little information on the clinical study on adjunctive efficacy of TCM on measles. Therefore, the objective of this study is to observe the adjunctive efficacy of TCM in the treatment of adult measles. Methods Ninety-one patients diagnosed with adult measles in our hospital were enrolled for this study. All of them underwent symptomatic treatment, nutritional support therapy, and ribavirin antiviral therapy. Loxoprofen was added to the treatment regime when the body temperature exceeded 38.5 °C. The patients were stratified into two groups based on the administration of TCM, comprising 49 individuals in the TCM group and 42 individuals in the control group. Patients in the TCM group voluntarily received the following TCM prescriptions: 15 g of Lonicerae Japonica, 15 g of Forsythiae Fructus, 15 g of Arnebiae Radix, 15 g of Cicadae Periostracum, 30 g of Phragmitis Rhizoma, 10 g of Anemarrhenae Rhizoma, 6 g of Glycyrrhizae Radix et Rhizoma and 30 g of Gypsum Fibrosum was administered to patients with high fever. Decoction: 1 dose daily for 5 days. The control group received treatment without the incorporation of TCM. Results In comparison to the control group, patients in the TCM group experienced a quicker resolution of clinical symptoms (P < 0.05) and a lower complication rate (P < 0.05). Conclusion The application of TCM in treating adult measles can shorten the duration of the disease, reduce the incidence of complications, and offers promise for wider clinical adoption and utilization.https://doi.org/10.1186/s41065-025-00518-0AdultsAntiviral drugsEfficacyMeaslesTraditional chinese medicine (TCM)
spellingShingle Xiaoyan Liu
Zhongying Bao
Shuhong Duan
Jing Sun
Jie Zhang
A retrospective study on the efficacy of integrating traditional Chinese medicine with Western medicine in the treatment of adult measles
Hereditas
Adults
Antiviral drugs
Efficacy
Measles
Traditional chinese medicine (TCM)
title A retrospective study on the efficacy of integrating traditional Chinese medicine with Western medicine in the treatment of adult measles
title_full A retrospective study on the efficacy of integrating traditional Chinese medicine with Western medicine in the treatment of adult measles
title_fullStr A retrospective study on the efficacy of integrating traditional Chinese medicine with Western medicine in the treatment of adult measles
title_full_unstemmed A retrospective study on the efficacy of integrating traditional Chinese medicine with Western medicine in the treatment of adult measles
title_short A retrospective study on the efficacy of integrating traditional Chinese medicine with Western medicine in the treatment of adult measles
title_sort retrospective study on the efficacy of integrating traditional chinese medicine with western medicine in the treatment of adult measles
topic Adults
Antiviral drugs
Efficacy
Measles
Traditional chinese medicine (TCM)
url https://doi.org/10.1186/s41065-025-00518-0
work_keys_str_mv AT xiaoyanliu aretrospectivestudyontheefficacyofintegratingtraditionalchinesemedicinewithwesternmedicineinthetreatmentofadultmeasles
AT zhongyingbao aretrospectivestudyontheefficacyofintegratingtraditionalchinesemedicinewithwesternmedicineinthetreatmentofadultmeasles
AT shuhongduan aretrospectivestudyontheefficacyofintegratingtraditionalchinesemedicinewithwesternmedicineinthetreatmentofadultmeasles
AT jingsun aretrospectivestudyontheefficacyofintegratingtraditionalchinesemedicinewithwesternmedicineinthetreatmentofadultmeasles
AT jiezhang aretrospectivestudyontheefficacyofintegratingtraditionalchinesemedicinewithwesternmedicineinthetreatmentofadultmeasles
AT xiaoyanliu retrospectivestudyontheefficacyofintegratingtraditionalchinesemedicinewithwesternmedicineinthetreatmentofadultmeasles
AT zhongyingbao retrospectivestudyontheefficacyofintegratingtraditionalchinesemedicinewithwesternmedicineinthetreatmentofadultmeasles
AT shuhongduan retrospectivestudyontheefficacyofintegratingtraditionalchinesemedicinewithwesternmedicineinthetreatmentofadultmeasles
AT jingsun retrospectivestudyontheefficacyofintegratingtraditionalchinesemedicinewithwesternmedicineinthetreatmentofadultmeasles
AT jiezhang retrospectivestudyontheefficacyofintegratingtraditionalchinesemedicinewithwesternmedicineinthetreatmentofadultmeasles