Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-Up
Background: To investigate functional and anatomical outcomes after pars plana vitrectomy (PPV) for lamellar macular hole (LMH) with a long-term follow-up. Methods: An interventional study on 14 patients (16 eyes) with LMH was conducted. The inclusion criteria included a minimum 36-month follow-up a...
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MDPI AG
2024-12-01
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| Online Access: | https://www.mdpi.com/2075-4418/15/1/27 |
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| author | Fabrizio Giansanti Cristina Nicolosi Giuseppe Ruben Barbera Giulio Vicini Flavia Lucarelli Edoardo Traniello Gradassi Vittoria Murro Gianni Virgili Daniela Bacherini |
| author_facet | Fabrizio Giansanti Cristina Nicolosi Giuseppe Ruben Barbera Giulio Vicini Flavia Lucarelli Edoardo Traniello Gradassi Vittoria Murro Gianni Virgili Daniela Bacherini |
| author_sort | Fabrizio Giansanti |
| collection | DOAJ |
| description | Background: To investigate functional and anatomical outcomes after pars plana vitrectomy (PPV) for lamellar macular hole (LMH) with a long-term follow-up. Methods: An interventional study on 14 patients (16 eyes) with LMH was conducted. The inclusion criteria included a minimum 36-month follow-up after PPV. The preoperative and postoperative best-corrected visual acuity (BCVA) and spectral domain optical coherence tomography parameters were examined. Results: Preoperatively, the mean BCVA was 0.46 ± 0.22 LogMAR. Epiretinal proliferation (ERP) was visible in 81.25% of eyes. Outer retinal disruption was present in 31.25% of LMH cases. The average central foveal thickness (CFT) measured 183.68 ± 61.73 microns. The mean BCVA improved at each follow-up time point: it was 0.24 ± 0.16 LogMAR at 1 month, 0.18 ± 0.15 LogMAR at 6 months, and 0.09 ± 0.11 LogMAR at the last follow-up. There was a statistically significant improvement between BCVA at 1 month and BCVA at 6 months and between BCVA at 6 months and BCVA at the last follow-up (<i>p</i> < 0.001). BCVA improved in all eyes, with 87.5% achieving at least 0.3 LogMAR improvement. The mean CFT at the 1-month follow-up was 211.45 ± 43.55 microns, increased to 248.81 ± 48.51 microns at 6 months, and further increased to 278.37 ± 45.50 microns at the last follow-up. Foveal contour restoration was achieved in all eyes, and those with preoperative ellipsoid zone alterations demonstrated a complete repair of the external retinal layers. No intra or postoperative complications were recorded. Conclusions: In our series, PPV had a high success rate and was associated with a substantial functional improvement in LMH treatment, and this result was maintained and kept increasing until the last follow-up. Long-term follow-up is crucial for a comprehensive evaluation of the healing process and to assess the benefits of the surgical intervention. |
| format | Article |
| id | doaj-art-be2eb7abf4134994b65b01e3b6604fc3 |
| institution | Kabale University |
| issn | 2075-4418 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
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| series | Diagnostics |
| spelling | doaj-art-be2eb7abf4134994b65b01e3b6604fc32025-01-10T13:16:29ZengMDPI AGDiagnostics2075-44182024-12-011512710.3390/diagnostics15010027Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-UpFabrizio Giansanti0Cristina Nicolosi1Giuseppe Ruben Barbera2Giulio Vicini3Flavia Lucarelli4Edoardo Traniello Gradassi5Vittoria Murro6Gianni Virgili7Daniela Bacherini8Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyEye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyEye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyDepartment of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, ItalyEye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyEye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyEye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyEye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyEye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Largo Brambilla 3, 50134 Florence, ItalyBackground: To investigate functional and anatomical outcomes after pars plana vitrectomy (PPV) for lamellar macular hole (LMH) with a long-term follow-up. Methods: An interventional study on 14 patients (16 eyes) with LMH was conducted. The inclusion criteria included a minimum 36-month follow-up after PPV. The preoperative and postoperative best-corrected visual acuity (BCVA) and spectral domain optical coherence tomography parameters were examined. Results: Preoperatively, the mean BCVA was 0.46 ± 0.22 LogMAR. Epiretinal proliferation (ERP) was visible in 81.25% of eyes. Outer retinal disruption was present in 31.25% of LMH cases. The average central foveal thickness (CFT) measured 183.68 ± 61.73 microns. The mean BCVA improved at each follow-up time point: it was 0.24 ± 0.16 LogMAR at 1 month, 0.18 ± 0.15 LogMAR at 6 months, and 0.09 ± 0.11 LogMAR at the last follow-up. There was a statistically significant improvement between BCVA at 1 month and BCVA at 6 months and between BCVA at 6 months and BCVA at the last follow-up (<i>p</i> < 0.001). BCVA improved in all eyes, with 87.5% achieving at least 0.3 LogMAR improvement. The mean CFT at the 1-month follow-up was 211.45 ± 43.55 microns, increased to 248.81 ± 48.51 microns at 6 months, and further increased to 278.37 ± 45.50 microns at the last follow-up. Foveal contour restoration was achieved in all eyes, and those with preoperative ellipsoid zone alterations demonstrated a complete repair of the external retinal layers. No intra or postoperative complications were recorded. Conclusions: In our series, PPV had a high success rate and was associated with a substantial functional improvement in LMH treatment, and this result was maintained and kept increasing until the last follow-up. Long-term follow-up is crucial for a comprehensive evaluation of the healing process and to assess the benefits of the surgical intervention.https://www.mdpi.com/2075-4418/15/1/27lamellar macular holepars plana vitrectomyfunctional outcomesanatomical outcomesmacular surgery |
| spellingShingle | Fabrizio Giansanti Cristina Nicolosi Giuseppe Ruben Barbera Giulio Vicini Flavia Lucarelli Edoardo Traniello Gradassi Vittoria Murro Gianni Virgili Daniela Bacherini Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-Up Diagnostics lamellar macular hole pars plana vitrectomy functional outcomes anatomical outcomes macular surgery |
| title | Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-Up |
| title_full | Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-Up |
| title_fullStr | Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-Up |
| title_full_unstemmed | Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-Up |
| title_short | Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-Up |
| title_sort | functional and anatomical outcomes of pars plana vitrectomy for lamellar macular hole long term follow up |
| topic | lamellar macular hole pars plana vitrectomy functional outcomes anatomical outcomes macular surgery |
| url | https://www.mdpi.com/2075-4418/15/1/27 |
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