Trophoblast Extracellular Vesicles as Modulators of Keratinocyte Stress Response and Senescence

Trophoblast Extracellular Vesicles as Modulators of Keratinocyte Stress Response and Senescence

Keratinocyte stress, caused by various intrinsic and extrinsic factors, contributes to the overall aging process. D-galactose-induced metabolic/oxidative stress is a commonly used <i>in vitro</i> model for studying premature aging. Due to their rich composition of bioactive molecules tha...

Full description

Saved in:

Bibliographic Details
Main Authors:	Mirjana Nacka-Aleksić, Andrea Pirković, Aleksandra Vilotić, Maja Kosanović, Dragana Dekanski, Janko Legner, Milica Jovanović Krivokuća
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Life
Subjects:	skin aging placenta wound healing regenerative medicine
Online Access:	https://www.mdpi.com/2075-1729/15/6/918
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

ELABELA targets the MEK/ERK axis to enhance trophoblast invasion in early-onset preeclampsia
by: Lijing Wang, et al.
Published: (2025-08-01)

Extracellular vesicles as prospective biological indicators for midgestational placental complications in the mouse
by: Elaine Lee, et al.
Published: (2025-07-01)

Prenylated chalcone analog-mediated Inhibition of Toxoplasma gondii growth in human trophoblast cell line and villous explants
by: Marina Paschoalino, et al.
Published: (2025-07-01)

Extravillous trophoblast invasion and decidualization in cesarean scar pregnancies
by: Lufen Gao, et al.
Published: (2022-10-01)

Vital role of autophagy flux inhibition of placental trophoblast cells in pregnancy disorders induced by HEV infection
by: Yifei Yang, et al.
Published: (2023-12-01)

Bioelectric characterization of senescing human keratinocytes
by: Hamid Sediqi, et al.
Published: (2025-09-01)

The Role of Oxidative Stress-Induced Senescence in the Pathogenesis of Preeclampsia
by: Alexandra Barbouti, et al.
Published: (2025-04-01)

M1/M2 macrophages: origin, phenotype, methods of production, interaction with natural killer cells and trophoblast
by: A. S. Zhguleva, et al.
Published: (2024-04-01)

The proteomic landscape of trophoblasts unravels calcium-dependent syncytialization processes and beta-chorionic gonadotropin (ß-hCG) production
by: Anna-Lena Gehl, et al.
Published: (2025-03-01)

Extracellular Vesicles: Recent Advances and Perspectives
by: Enrico Ragni
Published: (2025-05-01)

Placenta Accreta Spectrum (PAS) Disorders: Lessons Learned from the Introduction of Different Management Strategies in an Australian Tertiary Hospital. Retrospective Study (2004 to 2020)
by: Rita Caldas, et al.
Published: (2023-03-01)

Altered Production and Cellular Levels of Hydrogen Sulfide (H<sub>2</sub>S) in Placental Trophoblasts from Pregnancies Affected by Pre-Eclampsia
by: Xiaodan Chu, et al.
Published: (2025-03-01)

Urological Involvement in the Multidisciplinary Management of Placenta Accreta Spectrum in a Centralised, High-Volume Centre: A Retrospective Analysis
by: Brian D. Kelly, et al.
Published: (2022-01-01)

Bioprinted Hydrogels as Vehicles for the Application of Extracellular Vesicles in Regenerative Medicine
by: Marta Camacho-Cardenosa, et al.
Published: (2025-03-01)

Engineerable mesenchymal stem cell-derived extracellular vesicles as promising therapeutic strategies for pulmonary fibrosis
by: Yixiang Chen, et al.
Published: (2025-07-01)

Two Succenturiate Placentas in Dichorionic/Diamniotic (DC/DA) Twins – A Very Rare Case Presentation
by: B. Jeyamani, et al.
Published: (2025-01-01)

Dynamic shifts in trophoblast nucleos(t)ide metabolism, transport, and adenosine signaling during gestation and preterm birth
by: Mohammed Ali, et al.
Published: (2025-08-01)

Tumor Necrosis Factor-α Induced Cellular Stress on Trophoblastic Cells: NF-κB Signaling Could be a Potential Therapeutic Target
by: Erengül Tokay Varolli, et al.
Published: (2021-06-01)

MSC-Derived Extracellular Vesicles: Roles and Molecular Mechanisms for Tissue Repair
by: Wu T, et al.
Published: (2025-06-01)

Surgical management of delivery with placenta accreta spectrum from the perspective of perinatal obstetrics
by: A. Yu. Ralnikova, et al.
Published: (2024-11-01)

Clinical value of serum VEGF and sFlt-1 in pernicious placenta previa
by: Na Wang, et al.
Published: (2021-01-01)

The evolution of three generations of platelet concentrates products: a leap from classical formulations to the era of extracellular vesicles
by: Youan Li, et al.
Published: (2025-08-01)

External validation of and improvement upon a model for the prediction of placenta accreta spectrum severity using prospectively collected multicenter ultrasound data
by: Magdalena Kolak, et al.
Published: (2025-04-01)

Impact of dental pulp cells-derived small extracellular vesicles on the properties and behavior of dental pulp cells: an in-vitro study
by: Dina A. Hammouda, et al.
Published: (2025-05-01)

On the Issue of Optimizing Surgical Tactics and Blood-Saving Techniques in Case of Placenta Ingrowth Into the Uterine Scar
by: Z. D. Karimov, et al.
Published: (2023-07-01)

The accuracy of 3D-TUI and 3D power Doppler using Alalfy simple criteria in the diagnosis of placenta accreta spectrum
by: Mahmoud Alalfy, et al.
Published: (2021-10-01)

Porphyromonas gingivalis infection of oral keratinocytes drives the release of pro-inflammatory extracellular vesicles
by: Pierre-Yves Gegout, et al.
Published: (2025-07-01)

Morphological and immunohistochemical peculiarities of oncomarkers in placental barrier
by: T.D. Zadorozhnaya, et al.
Published: (2012-04-01)

The placenta — a Cinderella story
by: Colleen A. Wright
Published: (2007-07-01)

Estimated efficiency of uterine cavity suturing in patients during organ-preserving surgery with placenta increta while examining reproductive function in the postpartum period
by: E. A. Berg, et al.
Published: (2022-01-01)

Differentiating placenta accreta spectrum from scar dehiscence with underlying, non‐adherent placenta: A systematic review of scoring systems and primary data analysis
by: Theophilus K. Adu‐Bredu, et al.
Published: (2025-04-01)

Human umbilical cord mesenchymal stem cells-derived extracellular vesicles as a therapeutic approach to ameliorate bladder injury in animal models of radiation cystitis
by: Parmida Sadat Pezeshki, et al.
Published: (2025-07-01)

Barbed Suture versus Conventional Suture for Uterine Repair in Women with Placenta Accreta and Placenta Increta: A Retrospective Cohort Study
by: Ruihong Dong, et al.
Published: (2023-08-01)

Incidence And Risk Factors Of Maternal And Fetal Outcomes Among Patients Of Placenta Previa With And Without Placenta Accreta
by: Samina Naseem Khattak, et al.
Published: (2019-03-01)

PLACENTA ACCRETA – RISK FACTORS, SURGICAL AND CLINICAL OUTCOME
by: Mariana Tsankova, et al.
Published: (2025-03-01)

Frequency of Fetal Outcomes in Patients with Preexisting Placental Abnormalities. A Prospective Study in Tertiary Care Hospital
by: Niama Khan, et al.
Published: (2025-06-01)

Diploid fetus with partially triploid placenta: case presentation and management strategy
by: Behrokh Sahebdel, et al.
Published: (2024-12-01)

Clinical efficacy of aortic balloon occlusion during caesarean section in patients with placenta accreta spectrum disorders: a systematic review and meta-analysis
by: Yu Huang, et al.
Published: (2021-04-01)

Prevalence of fetal anomalies, stillbirth, neonatal morbidity, or mortality in pregnancies complicated by placenta accreta spectrum disorders
by: Pedro Viana Pinto, et al.
Published: (2025-04-01)

A scalable platform for EPSC-Induced MSC extracellular vesicles with therapeutic potential
by: Shixin Gong, et al.
Published: (2025-08-01)