Evaluation of Benzo[cd]indol‐2(1H)‐ones as Downstream Hedgehog Pathway Inhibitors
Abstract Epigenetic targeting of the Hedgehog (HH) signaling pathway has emerged as a possible strategy to combat HH pathway‐driven cancers. In this study, we report on benzo[cd]indol‐2(1H)‐ones as downstream Hedgehog pathway inhibitors. We find that benzo[cd]indol‐2(1H)‐one 1 has sub‐micromolar pot...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2025-05-01
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| Series: | ChemistryOpen |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/open.202500119 |
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