Impact of Gender on the Association of Epicardial Fat Thickness, Obesity, and Circadian Blood Pressure Pattern in Hypertensive Patients
This study aimed to investigate the effects of gender on the association between epicardial fat thickness (EFT) and circadian blood pressure (BP) changes in patients with recently diagnosed essential hypertension (EH). A total of 441 patients with EH (male/female: 236/205, mean age: 50.7 ± 13.8) and...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2015/924539 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841524744688500736 |
|---|---|
| author | In Kyoung Shim Kyoung-Im Cho Hyun-Su Kim Jung-Ho Heo Tae Joon Cha |
| author_facet | In Kyoung Shim Kyoung-Im Cho Hyun-Su Kim Jung-Ho Heo Tae Joon Cha |
| author_sort | In Kyoung Shim |
| collection | DOAJ |
| description | This study aimed to investigate the effects of gender on the association between epicardial fat thickness (EFT) and circadian blood pressure (BP) changes in patients with recently diagnosed essential hypertension (EH). A total of 441 patients with EH (male/female: 236/205, mean age: 50.7 ± 13.8) and 83 control patients underwent 24-hour ambulatory BP monitoring and echocardiography. Obese EH patients had higher circadian BP profile with BP variability, wall thickness, and left ventricular mass than nonobese EH patients and controls (all p’s <0.05) without gender differences. EFT was higher in female than in male patients (7.0 ± 2.5 versus 5.9 ± 2.2 mm, p<0.001) and higher in the obese female EH group (7.5 ± 2.6 mm) than in the control (6.4 ± 2.8 mm) or nonobese EH group (6.7 ± 2.8 mm) among women, whereas EFT did not vary among males (5.9 ± 1.9 versus 6.0 ± 2.7 versus 5.9 ± 2.4 mm, p=0.937). Multivariate logistic regression analysis demonstrated that the 24-hour mean BP variability was associated with SBP (p=0.018) and EFT (p=0.016) in female patients, but not in male patients. The relationships among circadian BP variability, obesity, and EFT were affected by gender in different manners. EFT may be a more valuable parameter in the evaluation of BP severity and obesity in women than in men. |
| format | Article |
| id | doaj-art-be14375defcb43e299430d2542bebf6e |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-be14375defcb43e299430d2542bebf6e2025-02-03T05:47:30ZengWileyJournal of Diabetes Research2314-67452314-67532015-01-01201510.1155/2015/924539924539Impact of Gender on the Association of Epicardial Fat Thickness, Obesity, and Circadian Blood Pressure Pattern in Hypertensive PatientsIn Kyoung Shim0Kyoung-Im Cho1Hyun-Su Kim2Jung-Ho Heo3Tae Joon Cha4Division of Cardiology, Department of Internal Medicine, Kosin University College of Medicine, Busan 602-702, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Kosin University College of Medicine, Busan 602-702, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Kosin University College of Medicine, Busan 602-702, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Kosin University College of Medicine, Busan 602-702, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Kosin University College of Medicine, Busan 602-702, Republic of KoreaThis study aimed to investigate the effects of gender on the association between epicardial fat thickness (EFT) and circadian blood pressure (BP) changes in patients with recently diagnosed essential hypertension (EH). A total of 441 patients with EH (male/female: 236/205, mean age: 50.7 ± 13.8) and 83 control patients underwent 24-hour ambulatory BP monitoring and echocardiography. Obese EH patients had higher circadian BP profile with BP variability, wall thickness, and left ventricular mass than nonobese EH patients and controls (all p’s <0.05) without gender differences. EFT was higher in female than in male patients (7.0 ± 2.5 versus 5.9 ± 2.2 mm, p<0.001) and higher in the obese female EH group (7.5 ± 2.6 mm) than in the control (6.4 ± 2.8 mm) or nonobese EH group (6.7 ± 2.8 mm) among women, whereas EFT did not vary among males (5.9 ± 1.9 versus 6.0 ± 2.7 versus 5.9 ± 2.4 mm, p=0.937). Multivariate logistic regression analysis demonstrated that the 24-hour mean BP variability was associated with SBP (p=0.018) and EFT (p=0.016) in female patients, but not in male patients. The relationships among circadian BP variability, obesity, and EFT were affected by gender in different manners. EFT may be a more valuable parameter in the evaluation of BP severity and obesity in women than in men.http://dx.doi.org/10.1155/2015/924539 |
| spellingShingle | In Kyoung Shim Kyoung-Im Cho Hyun-Su Kim Jung-Ho Heo Tae Joon Cha Impact of Gender on the Association of Epicardial Fat Thickness, Obesity, and Circadian Blood Pressure Pattern in Hypertensive Patients Journal of Diabetes Research |
| title | Impact of Gender on the Association of Epicardial Fat Thickness, Obesity, and Circadian Blood Pressure Pattern in Hypertensive Patients |
| title_full | Impact of Gender on the Association of Epicardial Fat Thickness, Obesity, and Circadian Blood Pressure Pattern in Hypertensive Patients |
| title_fullStr | Impact of Gender on the Association of Epicardial Fat Thickness, Obesity, and Circadian Blood Pressure Pattern in Hypertensive Patients |
| title_full_unstemmed | Impact of Gender on the Association of Epicardial Fat Thickness, Obesity, and Circadian Blood Pressure Pattern in Hypertensive Patients |
| title_short | Impact of Gender on the Association of Epicardial Fat Thickness, Obesity, and Circadian Blood Pressure Pattern in Hypertensive Patients |
| title_sort | impact of gender on the association of epicardial fat thickness obesity and circadian blood pressure pattern in hypertensive patients |
| url | http://dx.doi.org/10.1155/2015/924539 |
| work_keys_str_mv | AT inkyoungshim impactofgenderontheassociationofepicardialfatthicknessobesityandcircadianbloodpressurepatterninhypertensivepatients AT kyoungimcho impactofgenderontheassociationofepicardialfatthicknessobesityandcircadianbloodpressurepatterninhypertensivepatients AT hyunsukim impactofgenderontheassociationofepicardialfatthicknessobesityandcircadianbloodpressurepatterninhypertensivepatients AT junghoheo impactofgenderontheassociationofepicardialfatthicknessobesityandcircadianbloodpressurepatterninhypertensivepatients AT taejooncha impactofgenderontheassociationofepicardialfatthicknessobesityandcircadianbloodpressurepatterninhypertensivepatients |