Immunoinformatics design of a multi-epitope vaccine for Chlamydia trachomatis major outer membrane proteins

Immunoinformatics design of a multi-epitope vaccine for Chlamydia trachomatis major outer membrane proteins

Abstract Chlamydia trachomatis (CT) remains a significant infectious cause of blindness and sexually transmitted infections worldwide. The objective and novelty of this study lie in using different serovars of CT to design a broad-spectrum multi-epitope vaccine that might confer immunity against dif...

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Bibliographic Details
Main Authors: Seema Shetty, Swagatika Dash, Avinash Kumar, Shashidhar Vishwanath, Suvarna G. Kini, Angela Brand
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Multi-epitope vaccine
Chlamydia trachomatis
Immunoinformatics
T-cell and B-cell epitopes
Molecular dynamics simulations
Immune simulation
Online Access:https://doi.org/10.1038/s41598-024-81736-w
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