Experimental study of the effects of diazepam on vasospasm in a subarachnoid rat model through pathological and biochemical analysis

Experimental study of the effects of diazepam on vasospasm in a subarachnoid rat model through pathological and biochemical analysis

Abstract Subarachnoid hemorrhage (SAH), characterized by bleeding in the subarachnoid space, is associated with high morbidity and mortality, primarily due to cerebral vasospasm. Recent studies suggest oxidative stress and inflammation play crucial roles in vasospasm pathogenesis. This study investi...

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Bibliographic Details
Main Authors: Eyüp Çetin, Cumaali Demirtaş, Cansu Sönmez, Murat Yücel, Eray Metin Güler, Sarper Kocoğlu, Hakan Beyaztaş, Emine Demir
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Subarachnoid hemorrhage (SAH)
Cerebral vasospasm
Diazepam
Oxidative stress
Online Access:https://doi.org/10.1038/s41598-025-08325-3
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