Effect of preterm birth on blood pressure in later life: A systematic review and meta-analysis
Introduction: Preterm birth is linked to various complications in both infancy and adulthood. We assessed the association between preterm birth and hypertension in adulthood. Materials and Methods: PubMed, EMBASE, and Cochrane CENTRAL Register were searched for randomized controlled trials (RCT) com...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-11-01
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| Series: | Journal of Family Medicine and Primary Care |
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| Online Access: | https://journals.lww.com/10.4103/jfmpc.jfmpc_684_23 |
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| author | Abdulla K. Alsubai Mushtaq Ahmad Rabia Chang Mustafa A. Asghar Amna Siddiqui Hamza N. Khan Muhammad H. Ashraf Muhammad D. Javaid Asifa Kalwar Mahnoor Asad Kainat Memon Laibah A. Khan Amber Noorani Ahmed K. Siddiqi |
| author_facet | Abdulla K. Alsubai Mushtaq Ahmad Rabia Chang Mustafa A. Asghar Amna Siddiqui Hamza N. Khan Muhammad H. Ashraf Muhammad D. Javaid Asifa Kalwar Mahnoor Asad Kainat Memon Laibah A. Khan Amber Noorani Ahmed K. Siddiqi |
| author_sort | Abdulla K. Alsubai |
| collection | DOAJ |
| description | Introduction:
Preterm birth is linked to various complications in both infancy and adulthood. We assessed the association between preterm birth and hypertension in adulthood.
Materials and Methods:
PubMed, EMBASE, and Cochrane CENTRAL Register were searched for randomized controlled trials (RCT) comparing systolic and diastolic blood pressures in individuals born preterm and those born full-term, from inception till April 11th, 2022. Data were extracted, pooled, and analyzed. Forest plots were created for a visual demonstration.
Results:
Twenty-eight studies were included in our meta-analysis. SBP and DBP across all categories (Mean, Ambulatory, Daytime, and Nighttime) were higher in the preterm group compared to the term group. Mean SBP, mean ambulatory SBP, mean daytime SBP and mean nighttime SBP were 4.26 mmHg [95% CI: 3.09–5.43; P < 0.00001], 4.53 mmHg [95% CI: 1.82–7.24; P = 0.001], 4.51 mmHg [95% CI: 2.56–6.74; P < 0.00001], and 3.06 mmHg [95% CI: 1.32–4.80; P = 0.0006] higher in the preterm group, respectively. Mean DBP, mean ambulatory DBP, mean daytime DBP, and mean nighttime DBP were 2.32 mmHg [95% CI: 1.35–3.29; P < 0.00001], 1.54 mmHg [95% CI 0.68–2.39; P = 0.0004], 1.74 mmHg [95% CI: 0.92–2.56; P < 0.0001], and 1.58 mmHg [95% CI: 0.34–2.81; P = 0.01] higher in the preterm group, respectively.
Conclusion:
Our observations suggest that individuals who were born preterm may have higher blood pressures as compared to those who were born full-term. |
| format | Article |
| id | doaj-art-bd237ba464b944009f0cde45fbc2de7c |
| institution | Kabale University |
| issn | 2249-4863 2278-7135 |
| language | English |
| publishDate | 2023-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj-art-bd237ba464b944009f0cde45fbc2de7c2024-11-11T13:53:19ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352023-11-0112112805282610.4103/jfmpc.jfmpc_684_23Effect of preterm birth on blood pressure in later life: A systematic review and meta-analysisAbdulla K. AlsubaiMushtaq AhmadRabia ChangMustafa A. AsgharAmna SiddiquiHamza N. KhanMuhammad H. AshrafMuhammad D. JavaidAsifa KalwarMahnoor AsadKainat MemonLaibah A. KhanAmber NooraniAhmed K. SiddiqiIntroduction: Preterm birth is linked to various complications in both infancy and adulthood. We assessed the association between preterm birth and hypertension in adulthood. Materials and Methods: PubMed, EMBASE, and Cochrane CENTRAL Register were searched for randomized controlled trials (RCT) comparing systolic and diastolic blood pressures in individuals born preterm and those born full-term, from inception till April 11th, 2022. Data were extracted, pooled, and analyzed. Forest plots were created for a visual demonstration. Results: Twenty-eight studies were included in our meta-analysis. SBP and DBP across all categories (Mean, Ambulatory, Daytime, and Nighttime) were higher in the preterm group compared to the term group. Mean SBP, mean ambulatory SBP, mean daytime SBP and mean nighttime SBP were 4.26 mmHg [95% CI: 3.09–5.43; P < 0.00001], 4.53 mmHg [95% CI: 1.82–7.24; P = 0.001], 4.51 mmHg [95% CI: 2.56–6.74; P < 0.00001], and 3.06 mmHg [95% CI: 1.32–4.80; P = 0.0006] higher in the preterm group, respectively. Mean DBP, mean ambulatory DBP, mean daytime DBP, and mean nighttime DBP were 2.32 mmHg [95% CI: 1.35–3.29; P < 0.00001], 1.54 mmHg [95% CI 0.68–2.39; P = 0.0004], 1.74 mmHg [95% CI: 0.92–2.56; P < 0.0001], and 1.58 mmHg [95% CI: 0.34–2.81; P = 0.01] higher in the preterm group, respectively. Conclusion: Our observations suggest that individuals who were born preterm may have higher blood pressures as compared to those who were born full-term.https://journals.lww.com/10.4103/jfmpc.jfmpc_684_23adultblood pressuremeta-analysispremature birth |
| spellingShingle | Abdulla K. Alsubai Mushtaq Ahmad Rabia Chang Mustafa A. Asghar Amna Siddiqui Hamza N. Khan Muhammad H. Ashraf Muhammad D. Javaid Asifa Kalwar Mahnoor Asad Kainat Memon Laibah A. Khan Amber Noorani Ahmed K. Siddiqi Effect of preterm birth on blood pressure in later life: A systematic review and meta-analysis Journal of Family Medicine and Primary Care adult blood pressure meta-analysis premature birth |
| title | Effect of preterm birth on blood pressure in later life: A systematic review and meta-analysis |
| title_full | Effect of preterm birth on blood pressure in later life: A systematic review and meta-analysis |
| title_fullStr | Effect of preterm birth on blood pressure in later life: A systematic review and meta-analysis |
| title_full_unstemmed | Effect of preterm birth on blood pressure in later life: A systematic review and meta-analysis |
| title_short | Effect of preterm birth on blood pressure in later life: A systematic review and meta-analysis |
| title_sort | effect of preterm birth on blood pressure in later life a systematic review and meta analysis |
| topic | adult blood pressure meta-analysis premature birth |
| url | https://journals.lww.com/10.4103/jfmpc.jfmpc_684_23 |
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