Demystifying visual word form area visual and nonvisual response properties with precision fMRI
Summary: The visual word form area (VWFA) is a region in the left ventrotemporal cortex (VTC) whose specificity remains contentious. Using precision fMRI, we examine the VWFA’s responses to numerous visual and nonvisual stimuli, comparing them to adjacent category-selective visual regions and region...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
|
| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224027081 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846113093944344576 |
|---|---|
| author | Jin Li Kelly J. Hiersche Zeynep M. Saygin |
| author_facet | Jin Li Kelly J. Hiersche Zeynep M. Saygin |
| author_sort | Jin Li |
| collection | DOAJ |
| description | Summary: The visual word form area (VWFA) is a region in the left ventrotemporal cortex (VTC) whose specificity remains contentious. Using precision fMRI, we examine the VWFA’s responses to numerous visual and nonvisual stimuli, comparing them to adjacent category-selective visual regions and regions involved in language and attentional demand. We find that VWFA responds moderately to non-word visual stimuli, but is unique within VTC in its pronounced selectivity for visual words. Interestingly, the VWFA is also the only category-selective visual region engaged in auditory language, unlike the ubiquitous attentional demand effect throughout the VTC. However, this language selectivity is dwarfed by its visual responses even to nonpreferred categories, indicating the VWFA is not a core (amodal) language region. We also observed two additional auditory language VTC clusters, but these had no specificity for visual words. Our detailed investigation clarifies longstanding controversies about the landscape of visual and auditory language functionality within VTC. |
| format | Article |
| id | doaj-art-bcdcf2fac12543af9a02d9ff5820e3b8 |
| institution | Kabale University |
| issn | 2589-0042 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj-art-bcdcf2fac12543af9a02d9ff5820e3b82024-12-22T05:29:30ZengElsevieriScience2589-00422024-12-012712111481Demystifying visual word form area visual and nonvisual response properties with precision fMRIJin Li0Kelly J. Hiersche1Zeynep M. Saygin2Department of Psychology, The Ohio State University, Columbus, OH 43210, USA; Center for Cognitive and Behavioral Brain Imaging, The Ohio State University, Columbus, OH 43210, USA; School of Psychology, Georgia Institute of Technology, Atlanta, GA 30332, USA; Corresponding authorDepartment of Psychology, The Ohio State University, Columbus, OH 43210, USA; Center for Cognitive and Behavioral Brain Imaging, The Ohio State University, Columbus, OH 43210, USADepartment of Psychology, The Ohio State University, Columbus, OH 43210, USA; Center for Cognitive and Behavioral Brain Imaging, The Ohio State University, Columbus, OH 43210, USA; Corresponding authorSummary: The visual word form area (VWFA) is a region in the left ventrotemporal cortex (VTC) whose specificity remains contentious. Using precision fMRI, we examine the VWFA’s responses to numerous visual and nonvisual stimuli, comparing them to adjacent category-selective visual regions and regions involved in language and attentional demand. We find that VWFA responds moderately to non-word visual stimuli, but is unique within VTC in its pronounced selectivity for visual words. Interestingly, the VWFA is also the only category-selective visual region engaged in auditory language, unlike the ubiquitous attentional demand effect throughout the VTC. However, this language selectivity is dwarfed by its visual responses even to nonpreferred categories, indicating the VWFA is not a core (amodal) language region. We also observed two additional auditory language VTC clusters, but these had no specificity for visual words. Our detailed investigation clarifies longstanding controversies about the landscape of visual and auditory language functionality within VTC.http://www.sciencedirect.com/science/article/pii/S2589004224027081NeuroscienceSensory neuroscienceCognitive neuroscience |
| spellingShingle | Jin Li Kelly J. Hiersche Zeynep M. Saygin Demystifying visual word form area visual and nonvisual response properties with precision fMRI iScience Neuroscience Sensory neuroscience Cognitive neuroscience |
| title | Demystifying visual word form area visual and nonvisual response properties with precision fMRI |
| title_full | Demystifying visual word form area visual and nonvisual response properties with precision fMRI |
| title_fullStr | Demystifying visual word form area visual and nonvisual response properties with precision fMRI |
| title_full_unstemmed | Demystifying visual word form area visual and nonvisual response properties with precision fMRI |
| title_short | Demystifying visual word form area visual and nonvisual response properties with precision fMRI |
| title_sort | demystifying visual word form area visual and nonvisual response properties with precision fmri |
| topic | Neuroscience Sensory neuroscience Cognitive neuroscience |
| url | http://www.sciencedirect.com/science/article/pii/S2589004224027081 |
| work_keys_str_mv | AT jinli demystifyingvisualwordformareavisualandnonvisualresponsepropertieswithprecisionfmri AT kellyjhiersche demystifyingvisualwordformareavisualandnonvisualresponsepropertieswithprecisionfmri AT zeynepmsaygin demystifyingvisualwordformareavisualandnonvisualresponsepropertieswithprecisionfmri |