Transient reactivation of small ensembles of adult-born neurons during REM sleep supports memory consolidation in mice

Abstract While memory consolidation is widely believed to require memory reactivation synchronized with theta oscillations during REM sleep, direct causal evidence linking specific neuronal ensembles to this process has been lacking. Strong theta oscillations arise in the hippocampal dentate gyrus,...

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Main Authors: Sakthivel Srinivasan, Iyo Koyanagi, Pablo Vergara, Yuteng Wang, Akinobu Ohba, Toshie Naoi, Kaspar E. Vogt, Yoan Chérasse, Noriki Kutsumura, Takeshi Sakurai, Taro Tezuka, Masanori Sakaguchi
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62554-8
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