Updates from Gastrointestinal ASCO 2015

This year at ASCO GI we saw important data presented that has continued to shape the way we treat GI malignancies. Several important questions were addressed. Can we avoid surgery among patients with rectal tumors? Data from a provocative retrospective study indicated that certain subgroups of patie...

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Main Author: Shaheenah Dawood
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2015-01-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2015;volume=36;issue=2;spage=133;epage=136;aulast=Dawood
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author Shaheenah Dawood
author_facet Shaheenah Dawood
author_sort Shaheenah Dawood
collection DOAJ
description This year at ASCO GI we saw important data presented that has continued to shape the way we treat GI malignancies. Several important questions were addressed. Can we avoid surgery among patients with rectal tumors? Data from a provocative retrospective study indicated that certain subgroups of patients might not need surgery thereby preserving the rectum without compromising survival outcome. What is the role of ramicurumab among patients with advanced colorectal cancers? Data from the phase III RAISE trial revealed that the addition of ramicurumab to second line therapy significantly improved median overall survival. What is the role of immunotherapy in GI malignancies? Interesting results from the KEYNOTE-012 trial was presented that looked at the efficacy of pembriluzumab among patients with advanced gastric cancer with the investigators reporting interesting results of an objective response rate of 22.1% and a 6 months progression free survival of 24%. In this review we will briefly present these and other important highlights of the ASCO GI meeting.
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spelling doaj-art-bc842fea13c743a2bf36c6eace5bbd572025-08-20T03:52:07ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512015-01-0136213313610.4103/0971-5851.158852Updates from Gastrointestinal ASCO 2015Shaheenah DawoodThis year at ASCO GI we saw important data presented that has continued to shape the way we treat GI malignancies. Several important questions were addressed. Can we avoid surgery among patients with rectal tumors? Data from a provocative retrospective study indicated that certain subgroups of patients might not need surgery thereby preserving the rectum without compromising survival outcome. What is the role of ramicurumab among patients with advanced colorectal cancers? Data from the phase III RAISE trial revealed that the addition of ramicurumab to second line therapy significantly improved median overall survival. What is the role of immunotherapy in GI malignancies? Interesting results from the KEYNOTE-012 trial was presented that looked at the efficacy of pembriluzumab among patients with advanced gastric cancer with the investigators reporting interesting results of an objective response rate of 22.1% and a 6 months progression free survival of 24%. In this review we will briefly present these and other important highlights of the ASCO GI meeting.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2015;volume=36;issue=2;spage=133;epage=136;aulast=DawoodColorectal cancerpancreatic cancergastric cancer
spellingShingle Shaheenah Dawood
Updates from Gastrointestinal ASCO 2015
Indian Journal of Medical and Paediatric Oncology
Colorectal cancer
pancreatic cancer
gastric cancer
title Updates from Gastrointestinal ASCO 2015
title_full Updates from Gastrointestinal ASCO 2015
title_fullStr Updates from Gastrointestinal ASCO 2015
title_full_unstemmed Updates from Gastrointestinal ASCO 2015
title_short Updates from Gastrointestinal ASCO 2015
title_sort updates from gastrointestinal asco 2015
topic Colorectal cancer
pancreatic cancer
gastric cancer
url http://www.ijmpo.org/article.asp?issn=0971-5851;year=2015;volume=36;issue=2;spage=133;epage=136;aulast=Dawood
work_keys_str_mv AT shaheenahdawood updatesfromgastrointestinalasco2015