Demographics and clinical characteristics of a new population of centenarians in Colombia. The COOLCEN cohort

Aim: Centenarians represent a successful model of biological aging that is becoming increasingly common but still largely unknown. Data about centenarians in Colombia is scarce. The aim of this study was to provide a description of the demographic and clinical characteristics of a new cohort of cent...

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Main Authors: Ivan David Lozada-Martinez, Juan Sebastian Marín, Sandra Milena Castelblanco-Toro, Enrique A Mazenett-Granados, John Fredy Suárez, Mauricio Sarmiento, Juan-Manuel Anaya
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Archives of Gerontology and Geriatrics Plus
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950307824000031
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author Ivan David Lozada-Martinez
Juan Sebastian Marín
Sandra Milena Castelblanco-Toro
Enrique A Mazenett-Granados
John Fredy Suárez
Mauricio Sarmiento
Juan-Manuel Anaya
author_facet Ivan David Lozada-Martinez
Juan Sebastian Marín
Sandra Milena Castelblanco-Toro
Enrique A Mazenett-Granados
John Fredy Suárez
Mauricio Sarmiento
Juan-Manuel Anaya
author_sort Ivan David Lozada-Martinez
collection DOAJ
description Aim: Centenarians represent a successful model of biological aging that is becoming increasingly common but still largely unknown. Data about centenarians in Colombia is scarce. The aim of this study was to provide a description of the demographic and clinical characteristics of a new cohort of centenarians in Colombia. Methods: A retrospective, population-based cohort study was undertaken, employing a nationally validated registry provided by a health insurance company. Demographic information and prevalence rates of significant chronic diseases were evaluated. The geographical distribution of centenarians at the national level was mapped. Data were then compared with other age groups (>18-59 and 60-99 years-old), and with previous descriptions of centenarians. Results: Among the 2,362,436 persons included in the study, a prevalence of 0.12% centenarians was observed, of which 50.7% were female and the majority resides in urban areas (64.9%). Chronic diseases were observed in 275 (9.27%) centenarians, of whom 113 (3.81%) disclosed one chronic disease and 162 (5.46%) disclosed multimorbidity. The most prevalent chronic diseases were essential hypertension (8.6%), and chronic kidney disease (4.4%), which were significantly lower compared to others age groups. Centenarians were free of hematological, inflammatory arthritis, tuberculosis and human immunodeficiency virus infections. COVID-19 was observed in 2% of cases. Significant differences in health outcomes assessed were seen when comparing our results with centenarians from previously described blue zones. Conclusions: The COOLCEN cohort discloses a low prevalence of age-related chronic diseases, low economic status and no difference in gender distribution. The study will provide valuable insights into healthy aging, disease prevention, and improving the well-being of older adults.
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spelling doaj-art-bc7d1a4bc4f240398f84961b06430a002024-11-23T06:36:04ZengElsevierArchives of Gerontology and Geriatrics Plus2950-30782024-03-0111100006Demographics and clinical characteristics of a new population of centenarians in Colombia. The COOLCEN cohortIvan David Lozada-Martinez0Juan Sebastian Marín1Sandra Milena Castelblanco-Toro2Enrique A Mazenett-Granados3John Fredy Suárez4Mauricio Sarmiento5Juan-Manuel Anaya6Health Research and Innovation Center at Coosalud EPS, Cartagena, 130001, ColombiaHealth Research and Innovation Center at Coosalud EPS, Cartagena, 130001, Colombia; Population Health Management Group at Coosalud EPS, Cartagena, 130001, ColombiaIntellectus Memory and Cognition Center, Hospital Universitario San Ignacio, Institute of Aging, Faculty of Medicine, Pontificia Universidad Javeriana, Bogotá, ColombiaHealth Research and Innovation Center at Coosalud EPS, Cartagena, 130001, ColombiaPopulation Health Management Group at Coosalud EPS, Cartagena, 130001, ColombiaHealth Research and Innovation Center at Coosalud EPS, Cartagena, 130001, ColombiaHealth Research and Innovation Center at Coosalud EPS, Cartagena, 130001, Colombia; Corresponding author at: Health Research and Innovation Center at Coosalud EPS, Cra 2 N° 11-81, Edificio Murano, Cartagena, 130001, Colombia.Aim: Centenarians represent a successful model of biological aging that is becoming increasingly common but still largely unknown. Data about centenarians in Colombia is scarce. The aim of this study was to provide a description of the demographic and clinical characteristics of a new cohort of centenarians in Colombia. Methods: A retrospective, population-based cohort study was undertaken, employing a nationally validated registry provided by a health insurance company. Demographic information and prevalence rates of significant chronic diseases were evaluated. The geographical distribution of centenarians at the national level was mapped. Data were then compared with other age groups (>18-59 and 60-99 years-old), and with previous descriptions of centenarians. Results: Among the 2,362,436 persons included in the study, a prevalence of 0.12% centenarians was observed, of which 50.7% were female and the majority resides in urban areas (64.9%). Chronic diseases were observed in 275 (9.27%) centenarians, of whom 113 (3.81%) disclosed one chronic disease and 162 (5.46%) disclosed multimorbidity. The most prevalent chronic diseases were essential hypertension (8.6%), and chronic kidney disease (4.4%), which were significantly lower compared to others age groups. Centenarians were free of hematological, inflammatory arthritis, tuberculosis and human immunodeficiency virus infections. COVID-19 was observed in 2% of cases. Significant differences in health outcomes assessed were seen when comparing our results with centenarians from previously described blue zones. Conclusions: The COOLCEN cohort discloses a low prevalence of age-related chronic diseases, low economic status and no difference in gender distribution. The study will provide valuable insights into healthy aging, disease prevention, and improving the well-being of older adults.http://www.sciencedirect.com/science/article/pii/S2950307824000031CentenariansAgingHealthy agingColombiaMultimorbidity
spellingShingle Ivan David Lozada-Martinez
Juan Sebastian Marín
Sandra Milena Castelblanco-Toro
Enrique A Mazenett-Granados
John Fredy Suárez
Mauricio Sarmiento
Juan-Manuel Anaya
Demographics and clinical characteristics of a new population of centenarians in Colombia. The COOLCEN cohort
Archives of Gerontology and Geriatrics Plus
Centenarians
Aging
Healthy aging
Colombia
Multimorbidity
title Demographics and clinical characteristics of a new population of centenarians in Colombia. The COOLCEN cohort
title_full Demographics and clinical characteristics of a new population of centenarians in Colombia. The COOLCEN cohort
title_fullStr Demographics and clinical characteristics of a new population of centenarians in Colombia. The COOLCEN cohort
title_full_unstemmed Demographics and clinical characteristics of a new population of centenarians in Colombia. The COOLCEN cohort
title_short Demographics and clinical characteristics of a new population of centenarians in Colombia. The COOLCEN cohort
title_sort demographics and clinical characteristics of a new population of centenarians in colombia the coolcen cohort
topic Centenarians
Aging
Healthy aging
Colombia
Multimorbidity
url http://www.sciencedirect.com/science/article/pii/S2950307824000031
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