Assessment of microstructural abnormalities in gray and white matter of minimal hepatic encephalopathy patients using diffusion kurtosis imaging and their associations with neurocognitive dysfunction

Assessment of microstructural abnormalities in gray and white matter of minimal hepatic encephalopathy patients using diffusion kurtosis imaging and their associations with neurocognitive dysfunction

AimsAlthough neural activity abnormalities have been reported in cirrhosis patients with minimal hepatic encephalopathy (MHE), the neurophysiological mechanisms underlying microstructural brain alterations remain poorly understood. This prospective study aimed to assess microstructural abnormalities...

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Bibliographic Details
Main Authors: Qing Sun, Wenliang Fan, Yuan Liu, Zhifeng Kou, Ping Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Human Neuroscience
Subjects:
minimal hepatic encephalopathy
diffusion kurtosis imaging
tract-based spatial statistics
white matter
gray matter
voxel-based morphometry
Online Access:https://www.frontiersin.org/articles/10.3389/fnhum.2025.1600100/full
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