Case Report: Undifferentiated embryonic sarcoma of an adult liver

Undifferentiated embryonal sarcoma of the liver is a malignant mesenchymal tumor of the liver that predominantly affects children, with exceedingly rare occurrence in adults, and is associated with a poor prognosis. We present a case of undifferentiated embryonal sarcoma of the liver in a previously...

Full description

Saved in:
Bibliographic Details
Main Authors: Shengyong Li, Lexin Bao, Xiujun Li, Liang Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1599953/full
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Undifferentiated embryonal sarcoma of the liver is a malignant mesenchymal tumor of the liver that predominantly affects children, with exceedingly rare occurrence in adults, and is associated with a poor prognosis. We present a case of undifferentiated embryonal sarcoma of the liver in a previously healthy 45-year-old man admitted to our hospital due to fever. Magnetic resonance imaging revealed a cystic-solid mass in the right lobe of the liver, measuring approximately 15 * 13 * 13 cm in size. Imaging diagnosis raised a suspicion of biliary cystadenocarcinoma with hemorrhage. A hepatic resection was successfully performed, and the histologic diagnosis was undifferentiated embryonal sarcoma of the liver. The patient received a chemotherapy regimen of ifosfamide combined with epirubicin after surgery, and no recurrence was observed after 6 months of follow-up. We herein review the clinical, radiologic, and pathologic features of this rare tumor.
ISSN:2234-943X