Comfort efficacy of gene-transfected pig skin in arc burn patients
Objective To observe the comfort effect of gene-transfected pig skin in patients with arc burn wound. Methods A total of 56 patients with electric arc burn treated in our hospital from June 2020 to December 2022 were enrolled and then randomly divided into treatment group and control group, with 28...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of Army Medical University
2024-12-01
|
| Series: | 陆军军医大学学报 |
| Subjects: | |
| Online Access: | https://aammt.tmmu.edu.cn/html/202405078.htm |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846121528512479232 |
|---|---|
| author | WANG Qian DUAN Xuejing HA Hongwei |
| author_facet | WANG Qian DUAN Xuejing HA Hongwei |
| author_sort | WANG Qian |
| collection | DOAJ |
| description | Objective To observe the comfort effect of gene-transfected pig skin in patients with arc burn wound. Methods A total of 56 patients with electric arc burn treated in our hospital from June 2020 to December 2022 were enrolled and then randomly divided into treatment group and control group, with 28 cases in each group. Both groups were treated with debridement, including removing pollutants and necrotic skin, and cleaning the wounds with normal saline. After debridement, the shallow second-degree burn wounds in the control group were covered with silver ion functional antibacterial dressing and wrapped with sterile cotton pad, while those in the treatment group were covered with thawed and softened gene-transfected pig skins. For the deep second-degree burn wounds, after simple debridement, the wounds were treated with scab grinding in 48 h after burn when the condition of the patients was stable. After this, the wounds in the control group and the treatment group were treated as the shallow wounds, respectively. Visual Analogue Scale (VAS), State Anxiety Inventory (SAI) score, treatment process satisfaction, patient comfort and time for wound healing were observed and compared between the 2 groups. Results There was no significant difference in the VAS score and SAI score between the 2 groups at the first dressing change (P>0.05), but the VAS score and SAI score were obviously lower in the treatment group than the control group at the second and third dressing changes (P < 0.05). The treatment group obtained notably better comfort level and shorter time for wound healing than the control group (P < 0.05). Conclusion Gene-transfected pig skin shows good efficacy in the wound surface of arc burn, which can shorten the wound healing time, reduce the pain of dressing change and improve the satisfaction and comfort of patients.
|
| format | Article |
| id | doaj-art-bc47fba87a8145b3bffaec1f2ab7049f |
| institution | Kabale University |
| issn | 2097-0927 |
| language | zho |
| publishDate | 2024-12-01 |
| publisher | Editorial Office of Journal of Army Medical University |
| record_format | Article |
| series | 陆军军医大学学报 |
| spelling | doaj-art-bc47fba87a8145b3bffaec1f2ab7049f2024-12-16T01:31:08ZzhoEditorial Office of Journal of Army Medical University陆军军医大学学报2097-09272024-12-0146232649265410.16016/j.2097-0927.202405078Comfort efficacy of gene-transfected pig skin in arc burn patientsWANG Qian0DUAN Xuejing1 HA Hongwei2 First Department of Burn and Plastic Surgery, Tangshan Workers' Hospital, Tangshan, Hebei Province, 063000, China First Department of Burn and Plastic Surgery, Tangshan Workers' Hospital, Tangshan, Hebei Province, 063000, China First Department of Burn and Plastic Surgery, Tangshan Workers' Hospital, Tangshan, Hebei Province, 063000, ChinaObjective To observe the comfort effect of gene-transfected pig skin in patients with arc burn wound. Methods A total of 56 patients with electric arc burn treated in our hospital from June 2020 to December 2022 were enrolled and then randomly divided into treatment group and control group, with 28 cases in each group. Both groups were treated with debridement, including removing pollutants and necrotic skin, and cleaning the wounds with normal saline. After debridement, the shallow second-degree burn wounds in the control group were covered with silver ion functional antibacterial dressing and wrapped with sterile cotton pad, while those in the treatment group were covered with thawed and softened gene-transfected pig skins. For the deep second-degree burn wounds, after simple debridement, the wounds were treated with scab grinding in 48 h after burn when the condition of the patients was stable. After this, the wounds in the control group and the treatment group were treated as the shallow wounds, respectively. Visual Analogue Scale (VAS), State Anxiety Inventory (SAI) score, treatment process satisfaction, patient comfort and time for wound healing were observed and compared between the 2 groups. Results There was no significant difference in the VAS score and SAI score between the 2 groups at the first dressing change (P>0.05), but the VAS score and SAI score were obviously lower in the treatment group than the control group at the second and third dressing changes (P < 0.05). The treatment group obtained notably better comfort level and shorter time for wound healing than the control group (P < 0.05). Conclusion Gene-transfected pig skin shows good efficacy in the wound surface of arc burn, which can shorten the wound healing time, reduce the pain of dressing change and improve the satisfaction and comfort of patients. https://aammt.tmmu.edu.cn/html/202405078.htmgene-transfected pig skinarc burnpainhealing timecomfortsatisfaction degree |
| spellingShingle | WANG Qian DUAN Xuejing HA Hongwei Comfort efficacy of gene-transfected pig skin in arc burn patients 陆军军医大学学报 gene-transfected pig skin arc burn pain healing time comfort satisfaction degree |
| title | Comfort efficacy of gene-transfected pig skin in arc burn patients |
| title_full | Comfort efficacy of gene-transfected pig skin in arc burn patients |
| title_fullStr | Comfort efficacy of gene-transfected pig skin in arc burn patients |
| title_full_unstemmed | Comfort efficacy of gene-transfected pig skin in arc burn patients |
| title_short | Comfort efficacy of gene-transfected pig skin in arc burn patients |
| title_sort | comfort efficacy of gene transfected pig skin in arc burn patients |
| topic | gene-transfected pig skin arc burn pain healing time comfort satisfaction degree |
| url | https://aammt.tmmu.edu.cn/html/202405078.htm |
| work_keys_str_mv | AT wangqian comfortefficacyofgenetransfectedpigskininarcburnpatients AT duanxuejing comfortefficacyofgenetransfectedpigskininarcburnpatients AT hahongwei comfortefficacyofgenetransfectedpigskininarcburnpatients |