Risk factors for diabetic retinopathy in young and middle-aged patients: a retrospective study
Abstract Aims/Introduction To investigate the related risk factors of retinopathy in young and middle-aged diabetic patients in order to improve the prognosis of patients. Materials and Methods Using clinical practice data from a cohort study at our two research centers, we developed a bivariate log...
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BMC
2024-12-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-024-03821-y |
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| author | Zhihui Wang Xiaowen Bai Mengdi Wang Fei Li Tong Sun Wenjuan Liu Zhenghua Xu Dan Shen Lu Wang Meng li Lian cai Jinting Li Yongxia Ren |
| author_facet | Zhihui Wang Xiaowen Bai Mengdi Wang Fei Li Tong Sun Wenjuan Liu Zhenghua Xu Dan Shen Lu Wang Meng li Lian cai Jinting Li Yongxia Ren |
| author_sort | Zhihui Wang |
| collection | DOAJ |
| description | Abstract Aims/Introduction To investigate the related risk factors of retinopathy in young and middle-aged diabetic patients in order to improve the prognosis of patients. Materials and Methods Using clinical practice data from a cohort study at our two research centers, we developed a bivariate logistic regression model to investigate the frightening risk factors potentially for retinopathy in young and middle-aged patients with diabetes, including diabetes type, physical activity level, treatment-related characteristics and laboratory tests. Results A total of 453 patients with diabetes were investigated, 197 (43.5%) developed retinopathy. The risk of retinopathy was closely related to place of residence (OR: 0.275, 95% CI: 0.093–0.814), education level (OR: 0.522, 95% CI: 0.363–0.749), medical payment method (OR: 2.152, 95% CI: 1.308–3.539), BMI (OR: 1.187, 95% CI: 1.091–1.291), disease course (OR: 1.072, 95% CI: 1.028–1.118), hyperlipidemia (OR: 2.547, 95% CI: 1.260–5.150), physical activity level (OR: 0.312, 95% CI: 0.220–0.443), and dietary compliance (OR 0.871, 95% CI: 0.806–0.940). The area under the receiver operator characteristic curve was 0.915. Goodness of fit (Hosmer–Lemeshow) was 0.658. Conclusions The risk of young and middle-aged patients with increased as a result of certain patient characteristics and complications, especially lower dietary compliance and physical activity level. |
| format | Article |
| id | doaj-art-bc409897a1c34f76a14ac7698f74ef8c |
| institution | Kabale University |
| issn | 1471-2415 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj-art-bc409897a1c34f76a14ac7698f74ef8c2024-12-29T12:13:58ZengBMCBMC Ophthalmology1471-24152024-12-0124111010.1186/s12886-024-03821-yRisk factors for diabetic retinopathy in young and middle-aged patients: a retrospective studyZhihui Wang0Xiaowen Bai1Mengdi Wang2Fei Li3Tong Sun4Wenjuan Liu5Zhenghua Xu6Dan Shen7Lu Wang8Meng li9Lian cai10Jinting Li11Yongxia Ren12Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Nankai Hospital, Tianjin Medical University Nankai Hospital, Tianjin Key Lab of Acute Abdomen Disease Associated Organ Injury and ITCWM RepairTianjin Nankai Hospital, Tianjin Medical University Nankai Hospital, Tianjin Key Lab of Acute Abdomen Disease Associated Organ Injury and ITCWM RepairTianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual ScienceTianjin Nankai Hospital, Tianjin Medical University Nankai Hospital, Tianjin Key Lab of Acute Abdomen Disease Associated Organ Injury and ITCWM RepairTianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual ScienceAbstract Aims/Introduction To investigate the related risk factors of retinopathy in young and middle-aged diabetic patients in order to improve the prognosis of patients. Materials and Methods Using clinical practice data from a cohort study at our two research centers, we developed a bivariate logistic regression model to investigate the frightening risk factors potentially for retinopathy in young and middle-aged patients with diabetes, including diabetes type, physical activity level, treatment-related characteristics and laboratory tests. Results A total of 453 patients with diabetes were investigated, 197 (43.5%) developed retinopathy. The risk of retinopathy was closely related to place of residence (OR: 0.275, 95% CI: 0.093–0.814), education level (OR: 0.522, 95% CI: 0.363–0.749), medical payment method (OR: 2.152, 95% CI: 1.308–3.539), BMI (OR: 1.187, 95% CI: 1.091–1.291), disease course (OR: 1.072, 95% CI: 1.028–1.118), hyperlipidemia (OR: 2.547, 95% CI: 1.260–5.150), physical activity level (OR: 0.312, 95% CI: 0.220–0.443), and dietary compliance (OR 0.871, 95% CI: 0.806–0.940). The area under the receiver operator characteristic curve was 0.915. Goodness of fit (Hosmer–Lemeshow) was 0.658. Conclusions The risk of young and middle-aged patients with increased as a result of certain patient characteristics and complications, especially lower dietary compliance and physical activity level.https://doi.org/10.1186/s12886-024-03821-yRetinopathyDiabetesRisk factorsPrediction model |
| spellingShingle | Zhihui Wang Xiaowen Bai Mengdi Wang Fei Li Tong Sun Wenjuan Liu Zhenghua Xu Dan Shen Lu Wang Meng li Lian cai Jinting Li Yongxia Ren Risk factors for diabetic retinopathy in young and middle-aged patients: a retrospective study BMC Ophthalmology Retinopathy Diabetes Risk factors Prediction model |
| title | Risk factors for diabetic retinopathy in young and middle-aged patients: a retrospective study |
| title_full | Risk factors for diabetic retinopathy in young and middle-aged patients: a retrospective study |
| title_fullStr | Risk factors for diabetic retinopathy in young and middle-aged patients: a retrospective study |
| title_full_unstemmed | Risk factors for diabetic retinopathy in young and middle-aged patients: a retrospective study |
| title_short | Risk factors for diabetic retinopathy in young and middle-aged patients: a retrospective study |
| title_sort | risk factors for diabetic retinopathy in young and middle aged patients a retrospective study |
| topic | Retinopathy Diabetes Risk factors Prediction model |
| url | https://doi.org/10.1186/s12886-024-03821-y |
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