Prevalence of Undernutrition Among Children and Adolescents with Cancer Living in Sub-Saharan African Countries: A Systematic Review and Meta-analysis
Objective . To systematically review studies to provide the pooled estimate of undernutrition among children and adolescents with cancer living in sub-Saharan African countries. Methods . The review followed the recommendations outlined in the PRISMA statement. Online searches were performed on elec...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2024-11-01
|
| Series: | Global Pediatric Health |
| Online Access: | https://doi.org/10.1177/2333794X241298807 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846155294625759232 |
|---|---|
| author | Berhanu Mengistu MSc Aysheshim Kassahun Belew MSc Lemlem Daniel Baffa MPH Elsa Awoke Fentie MPH Muluken Chanie Agimas MPH Ever Siyoum Shewarega MPH Esmael Ali Muhammed MSc Mekuriaw Nibret Aweke MPH |
| author_facet | Berhanu Mengistu MSc Aysheshim Kassahun Belew MSc Lemlem Daniel Baffa MPH Elsa Awoke Fentie MPH Muluken Chanie Agimas MPH Ever Siyoum Shewarega MPH Esmael Ali Muhammed MSc Mekuriaw Nibret Aweke MPH |
| author_sort | Berhanu Mengistu MSc |
| collection | DOAJ |
| description | Objective . To systematically review studies to provide the pooled estimate of undernutrition among children and adolescents with cancer living in sub-Saharan African countries. Methods . The review followed the recommendations outlined in the PRISMA statement. Online searches were performed on electronic databases such as PubMed, Scopus, Embase, and Hinari; gray literature sources: such as Google, Google Scholar, and university repositories were also searched. A random effect model was used to drive the pooled prevalence, and was reported at a 95% Confidence Interval (CI). Heterogeneity was assessed using subgroup analysis and univariable meta-regression. The effect of each study on the overall prevalence was assessed using leave-one-out sensitivity analysis. In all the models, statistical significance was set at P -value <.05. Result . A total of 623 articles were identified, and 21 articles were retrieved for the final analysis. The overall pooled prevalence of undernutrition was 41.34% (95% CI: 31.64%, 51.04%). The highest prevalence of undernutrition was observed from studies that used Arm Muscle Area (AMC) for age to assess undernutrition: 61.66% (95% CI: 47.59%, 75.72%). The protocol for this review has been registered at PROSPERO (CRD42024510052). Conclusion . The prevalence of undernutrition in sub-Saharan African countries was considerably high. Therefore, policy directions and cost-effective approaches that sustainably address undernutrition among pediatric patients with cancers are needed. |
| format | Article |
| id | doaj-art-bc3f2b68d71c44dc958440741ca0644a |
| institution | Kabale University |
| issn | 2333-794X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Global Pediatric Health |
| spelling | doaj-art-bc3f2b68d71c44dc958440741ca0644a2024-11-26T13:03:33ZengSAGE PublishingGlobal Pediatric Health2333-794X2024-11-011110.1177/2333794X241298807Prevalence of Undernutrition Among Children and Adolescents with Cancer Living in Sub-Saharan African Countries: A Systematic Review and Meta-analysisBerhanu Mengistu MSc0Aysheshim Kassahun Belew MSc1Lemlem Daniel Baffa MPH2Elsa Awoke Fentie MPH3Muluken Chanie Agimas MPH4Ever Siyoum Shewarega MPH5Esmael Ali Muhammed MSc6Mekuriaw Nibret Aweke MPH7Department of Human Nutrition, Institute of Public Health, University of Gondar, Gondar, EthiopiaDepartment of Human Nutrition, Institute of Public Health, University of Gondar, Gondar, EthiopiaDepartment of Human Nutrition, Institute of Public Health, University of Gondar, Gondar, EthiopiaDepartment of Reproductive Health, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartment of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaDepartment of Reproductive Health, School of Public Health, College of Medicine and Health Sciences, Dilla University, Dilla, EthiopiaDepartment of Human Nutrition, Institute of Public Health, University of Gondar, Gondar, EthiopiaDepartment of Human Nutrition, Institute of Public Health, University of Gondar, Gondar, EthiopiaObjective . To systematically review studies to provide the pooled estimate of undernutrition among children and adolescents with cancer living in sub-Saharan African countries. Methods . The review followed the recommendations outlined in the PRISMA statement. Online searches were performed on electronic databases such as PubMed, Scopus, Embase, and Hinari; gray literature sources: such as Google, Google Scholar, and university repositories were also searched. A random effect model was used to drive the pooled prevalence, and was reported at a 95% Confidence Interval (CI). Heterogeneity was assessed using subgroup analysis and univariable meta-regression. The effect of each study on the overall prevalence was assessed using leave-one-out sensitivity analysis. In all the models, statistical significance was set at P -value <.05. Result . A total of 623 articles were identified, and 21 articles were retrieved for the final analysis. The overall pooled prevalence of undernutrition was 41.34% (95% CI: 31.64%, 51.04%). The highest prevalence of undernutrition was observed from studies that used Arm Muscle Area (AMC) for age to assess undernutrition: 61.66% (95% CI: 47.59%, 75.72%). The protocol for this review has been registered at PROSPERO (CRD42024510052). Conclusion . The prevalence of undernutrition in sub-Saharan African countries was considerably high. Therefore, policy directions and cost-effective approaches that sustainably address undernutrition among pediatric patients with cancers are needed.https://doi.org/10.1177/2333794X241298807 |
| spellingShingle | Berhanu Mengistu MSc Aysheshim Kassahun Belew MSc Lemlem Daniel Baffa MPH Elsa Awoke Fentie MPH Muluken Chanie Agimas MPH Ever Siyoum Shewarega MPH Esmael Ali Muhammed MSc Mekuriaw Nibret Aweke MPH Prevalence of Undernutrition Among Children and Adolescents with Cancer Living in Sub-Saharan African Countries: A Systematic Review and Meta-analysis Global Pediatric Health |
| title | Prevalence of Undernutrition Among Children and Adolescents with Cancer Living in Sub-Saharan African Countries: A Systematic Review and Meta-analysis |
| title_full | Prevalence of Undernutrition Among Children and Adolescents with Cancer Living in Sub-Saharan African Countries: A Systematic Review and Meta-analysis |
| title_fullStr | Prevalence of Undernutrition Among Children and Adolescents with Cancer Living in Sub-Saharan African Countries: A Systematic Review and Meta-analysis |
| title_full_unstemmed | Prevalence of Undernutrition Among Children and Adolescents with Cancer Living in Sub-Saharan African Countries: A Systematic Review and Meta-analysis |
| title_short | Prevalence of Undernutrition Among Children and Adolescents with Cancer Living in Sub-Saharan African Countries: A Systematic Review and Meta-analysis |
| title_sort | prevalence of undernutrition among children and adolescents with cancer living in sub saharan african countries a systematic review and meta analysis |
| url | https://doi.org/10.1177/2333794X241298807 |
| work_keys_str_mv | AT berhanumengistumsc prevalenceofundernutritionamongchildrenandadolescentswithcancerlivinginsubsaharanafricancountriesasystematicreviewandmetaanalysis AT aysheshimkassahunbelewmsc prevalenceofundernutritionamongchildrenandadolescentswithcancerlivinginsubsaharanafricancountriesasystematicreviewandmetaanalysis AT lemlemdanielbaffamph prevalenceofundernutritionamongchildrenandadolescentswithcancerlivinginsubsaharanafricancountriesasystematicreviewandmetaanalysis AT elsaawokefentiemph prevalenceofundernutritionamongchildrenandadolescentswithcancerlivinginsubsaharanafricancountriesasystematicreviewandmetaanalysis AT mulukenchanieagimasmph prevalenceofundernutritionamongchildrenandadolescentswithcancerlivinginsubsaharanafricancountriesasystematicreviewandmetaanalysis AT eversiyoumshewaregamph prevalenceofundernutritionamongchildrenandadolescentswithcancerlivinginsubsaharanafricancountriesasystematicreviewandmetaanalysis AT esmaelalimuhammedmsc prevalenceofundernutritionamongchildrenandadolescentswithcancerlivinginsubsaharanafricancountriesasystematicreviewandmetaanalysis AT mekuriawnibretawekemph prevalenceofundernutritionamongchildrenandadolescentswithcancerlivinginsubsaharanafricancountriesasystematicreviewandmetaanalysis |