The application study of harmonization code in medical device adverse event reporting

Abstract Background The reporting of adverse events in medical devices (MD) is a starting point of post-market surveillance and the most common source of initial safety signals. Because MD adverse events (AE) occur globally and involve high-profile international public health crises, international r...

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Main Authors: Soo Jeong Choi, Sooin Choi, Songhyeon Park, Ki Chang Nam, Hye Jung Jang, Jin Kuk Kim, You Kyoung Lee, Hiroshi Ishikawa, Eric Woo
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Health Services Research
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Online Access:https://doi.org/10.1186/s12913-024-11885-1
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author Soo Jeong Choi
Sooin Choi
Songhyeon Park
Ki Chang Nam
Hye Jung Jang
Jin Kuk Kim
You Kyoung Lee
Hiroshi Ishikawa
Eric Woo
author_facet Soo Jeong Choi
Sooin Choi
Songhyeon Park
Ki Chang Nam
Hye Jung Jang
Jin Kuk Kim
You Kyoung Lee
Hiroshi Ishikawa
Eric Woo
author_sort Soo Jeong Choi
collection DOAJ
description Abstract Background The reporting of adverse events in medical devices (MD) is a starting point of post-market surveillance and the most common source of initial safety signals. Because MD adverse events (AE) occur globally and involve high-profile international public health crises, international regulators implanted standard codes for MDAE reporting. This study aimed to assess the application of MDAE terminology and codes by providing examples of virtual events. Methods An online survey was conducted among participants of the MD Training Program for Regulatory Authorities which provide International Medical Device Regulators Forum (IMDRF) adverse event terminology and codes, and six virtual MDAE cases. Results All 29 of the 72 participants were regulators. In all cases, most participants selected the broad (level 1) codes rather than the detailed (level 2 or level 3) codes. While responders selected a variety of codes for all annexes in case 1, over 50% of responders selected the intended codes in case 6. The codes for cause investigation were chosen more frequently than other annexes for device problem, components, and health effect. No differences were observed in code selection amongst different stakeholders. Conclusions We identified the diversification in terminology and code selection for reporting MDAEs.
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series BMC Health Services Research
spelling doaj-art-bc37bc1ccc294561bb9e4f89c91dc6822024-11-17T12:17:00ZengBMCBMC Health Services Research1472-69632024-11-0124111110.1186/s12913-024-11885-1The application study of harmonization code in medical device adverse event reportingSoo Jeong Choi0Sooin Choi1Songhyeon Park2Ki Chang Nam3Hye Jung Jang4Jin Kuk Kim5You Kyoung Lee6Hiroshi Ishikawa7Eric Woo8Division of Nephrology, Department of Internal Medicine, Soonchunhyang University College of MedicineCenter for Medical Device Safety Information Monitoring, Soonchunhyang University Bucheon HospitalSoonchunhyang Medical Device Clinical Research Center, Soonchunhyang UniversityDepartment of Medical Engineering, Dongguk University College of MedicineDepartment of Medical Devices, Clinical Trial Center, Yonsei University Health System Severance HospitalDivision of Nephrology, Department of Internal Medicine, Soonchunhyang University College of MedicineCenter for Medical Device Safety Information Monitoring, Soonchunhyang University Bucheon HospitalAdvanced Biomedical Research, University of YamanashiECRI InstituteAbstract Background The reporting of adverse events in medical devices (MD) is a starting point of post-market surveillance and the most common source of initial safety signals. Because MD adverse events (AE) occur globally and involve high-profile international public health crises, international regulators implanted standard codes for MDAE reporting. This study aimed to assess the application of MDAE terminology and codes by providing examples of virtual events. Methods An online survey was conducted among participants of the MD Training Program for Regulatory Authorities which provide International Medical Device Regulators Forum (IMDRF) adverse event terminology and codes, and six virtual MDAE cases. Results All 29 of the 72 participants were regulators. In all cases, most participants selected the broad (level 1) codes rather than the detailed (level 2 or level 3) codes. While responders selected a variety of codes for all annexes in case 1, over 50% of responders selected the intended codes in case 6. The codes for cause investigation were chosen more frequently than other annexes for device problem, components, and health effect. No differences were observed in code selection amongst different stakeholders. Conclusions We identified the diversification in terminology and code selection for reporting MDAEs.https://doi.org/10.1186/s12913-024-11885-1Medical devicesSafety managementAdverse eventPost-market surveillanceIMDRFInternational medical device regulators forum
spellingShingle Soo Jeong Choi
Sooin Choi
Songhyeon Park
Ki Chang Nam
Hye Jung Jang
Jin Kuk Kim
You Kyoung Lee
Hiroshi Ishikawa
Eric Woo
The application study of harmonization code in medical device adverse event reporting
BMC Health Services Research
Medical devices
Safety management
Adverse event
Post-market surveillance
IMDRF
International medical device regulators forum
title The application study of harmonization code in medical device adverse event reporting
title_full The application study of harmonization code in medical device adverse event reporting
title_fullStr The application study of harmonization code in medical device adverse event reporting
title_full_unstemmed The application study of harmonization code in medical device adverse event reporting
title_short The application study of harmonization code in medical device adverse event reporting
title_sort application study of harmonization code in medical device adverse event reporting
topic Medical devices
Safety management
Adverse event
Post-market surveillance
IMDRF
International medical device regulators forum
url https://doi.org/10.1186/s12913-024-11885-1
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